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Literature summary extracted from
- Purification and characterization of a digestive cathepsin D proteinase isolated from Tribolium castaneum larvae (Herbst) (1996), Insect Biochem. Mol. Biol., 26, 95-100.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.23.5 | Monoiodoacetic acid | - |
Tribolium castaneum |  |
| 3.4.23.5 | pepstatin | pepstatin A | Tribolium castaneum | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.23.5 | 22000 | - |
x * 22000, SDS-PAGE | Tribolium castaneum |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.23.5 | Tribolium castaneum | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.23.5 | no modification | enzyme contains no carbohydrate | Tribolium castaneum |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.23.5 | partial | Tribolium castaneum |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.23.5 | larva | - |
Tribolium castaneum | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.23.5 | additional information | - |
- |
Tribolium castaneum |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 3.4.23.5 | -80°C, stable | Tribolium castaneum |
| 3.4.23.5 | 4°C, complete loss of activity after 72 h | Tribolium castaneum |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.23.5 | Albumin + H2O | no activity with bovine serum albumin | Tribolium castaneum | ? | - |
? | |
| 3.4.23.5 | Hemoglobin + H2O | - |
Tribolium castaneum | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.23.5 | ? | x * 22000, SDS-PAGE | Tribolium castaneum |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.23.5 | 4 | - |
72 h, complete loss of activity | Tribolium castaneum |
| 3.4.23.5 | 55 | - |
15 min, more than 50% loss of activity | Tribolium castaneum |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.23.5 | 3 | - |
- |
Tribolium castaneum |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.23.5 | 2 | 3.5 | about 65% of maximal activity at pH 2.0 and at pH 3.5 | Tribolium castaneum |
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Release 2023.1 (January 2023)
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