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Literature summary extracted from
- L-myo-Inositol-1-phosphate synthase from bovine testis (1982), Methods Enzymol., 90, 309-314.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.5.1.4 | NH4+ | stimulates | Bos taurus |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.5.1.4 | 2-Deoxy-2-fluoroglucose 6-phosphate | - |
Bos taurus | |
| 5.5.1.4 | 2-deoxy-D-glucose 6-phosphate | - |
Bos taurus | |
| 5.5.1.4 | Cd2+ | - |
Bos taurus | |
| 5.5.1.4 | Cu2+ | - |
Bos taurus | |
| 5.5.1.4 | D-mannose 6-phosphate | - |
Bos taurus | |
| 5.5.1.4 | EDTA | no inhibition | Bos taurus | |
| 5.5.1.4 | Na+ | - |
Bos taurus | |
| 5.5.1.4 | Zn2+ | - |
Bos taurus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.5.1.4 | K+ | stimulates 2fold and with added K+, 2.5fold | Bos taurus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 5.5.1.4 | 209000 | - |
equilibrium centrifugation | Bos taurus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.5.1.4 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.5.1.4 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.5.1.4 | testis | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.5.1.4 | 2-deoxy-D-glucose 6-phosphate | at 11.5% of the activity relative to D-glucose 6-phosphate | Bos taurus | 5-deoxy-L-myo-inositol 1-phosphate | - |
? | |
| 5.5.1.4 | D-2-Deoxy-2-fluoroglucose 6-phosphate | at 0.2% of the activity relative to D-glucose 6-phosphate | Bos taurus | 5-Deoxy-5-fluoro-myo-inositol 1-phosphate | - |
? | |
| 5.5.1.4 | D-Glucose 6-phosphate | - |
Bos taurus | L-myo-Inositol 1-phosphate | - |
? | |
| 5.5.1.4 | D-Mannose 6-phosphate | at 11.5% of the activity relative to D-glucose 6-phosphate | Bos taurus | myo-Inositol 1-phosphate | - |
? | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.5.1.4 | NAD+ | cofactor, Km: 0.011 mM | Bos taurus | |
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Release 2023.1 (January 2023)
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