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Literature summary extracted from

  • Swanson, A.A.; Martin, B.J.; Spicer, S.S.
    Human placental cathepsin B1. Isolation and some physical properties (1974), Biochem. J., 137, 223-228.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.22.1 cysteine activates Homo sapiens
3.4.22.1 dithiothreitol activates Homo sapiens

General Stability

EC Number General Stability Organism
3.4.22.1 unstable in absence of thiol compounds Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.1 Cu2+
-
 Homo sapiens
3.4.22.1 Hg2+
-
 Homo sapiens
3.4.22.1 iodoacetic acid
-
 Homo sapiens
3.4.22.1 N-ethylmaleimide
-
 Homo sapiens
3.4.22.1 N-tosyl-lysyl chloromethylketone
-
 Homo sapiens
3.4.22.1 p-chloromercuribenzoate
-
 Homo sapiens
3.4.22.1 Zn2+
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.22.1 24250
-
 sedimentation equilibrium centrifugation Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.22.1 Proteins + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.1 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.22.1
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.1 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.1 benzoyl-arginine ethyl ester + H2O
-
 Homo sapiens benzoyl-arginine + ethanol
-
 ?
3.4.22.1 benzoyl-DL-Arg-beta-naphthylamide + H2O
-
 Homo sapiens benzoyl-DL-Arg + beta-naphthylamine
-
 ?
3.4.22.1 benzoyl-DL-Arg-p-nitroanilide + H2O
-
 Homo sapiens benzoyl-DL-Arg + p-nitroaniline
-
 ?
3.4.22.1 benzoyl-DL-argininamide + H2O
-
 Homo sapiens benzoyl-DL-arginine + NH3
-
 ?
3.4.22.1 denatured hemoglobin + H2O
-
 Homo sapiens hydrolyzed denatured hemoglobin
-
 ?
3.4.22.1 myoglobin + H2O
-
 Homo sapiens hydrolyzed myoglobin
-
 ?
3.4.22.1 Proteins + H2O
-
 Homo sapiens ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.22.1 37 40
-
 Homo sapiens

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
3.4.22.1 30 55
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.22.1 5.5
-
-
 Homo sapiens

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
3.4.22.1 3.6 6.5
-
 Homo sapiens