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Literature summary extracted from
- Sequencing and cloning of human prolylcarboxypeptidase (angiotensinase C). Similarity to both serine carboxypeptidase and prolylendopeptidase families [published erratum appears in J Biol Chem 1993 Dec 5;268(34):26032 (1993), J. Biol. Chem., 268, 16631-16638.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.16.2 | - |
Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.16.2 | diisopropyl fluorophosphate | - |
Homo sapiens |  |
| 3.4.16.2 | N-benzyloxycarbonyl-Pro-prolinal | - |
Homo sapiens | |
| 3.4.16.2 | p-chloromercuriphenylsulfonic acid | 1 mM, 15% inhibition | Homo sapiens | |
| 3.4.16.2 | PCMB | 1 mM, 15% inhibition | Homo sapiens | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.16.2 | lysosome | - |
Homo sapiens | 5764 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.16.2 | 51043 | - |
x * 51043, calculation from nucleotide sequence | Homo sapiens |
| 3.4.16.2 | 58000 | - |
x * 58000, SDS-PAGE | Homo sapiens |
| 3.4.16.2 | 110000 | - |
gel filtration | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.16.2 | Homo sapiens | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.16.2 | glycoprotein | contains 12% carbohydrate per weight | Homo sapiens |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.16.2 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.16.2 | kidney | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.16.2 | angiotensin II + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.16.2 | angiotensin III + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.16.2 | [des-Arg9]bradykinin + H2O | - |
Homo sapiens | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.16.2 | ? | x * 58000, SDS-PAGE | Homo sapiens |
| 3.4.16.2 | ? | x * 51043, calculation from nucleotide sequence | Homo sapiens |
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