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Literature summary extracted from
- Dipeptidyl peptidase III is a zinc metallo-exopeptidase (1998), Biochem. J., 329, 275-282.
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 3.4.14.4 | H450Y | no activity | Homo sapiens |
| 3.4.14.4 | H455Y | no activity | Homo sapiens |
| 3.4.14.4 | Q451A | no activity | Homo sapiens |
| 3.4.14.4 | Q451D | no activity | Homo sapiens |
| 3.4.14.4 | Q508A | no activity | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.14.4 | 3,4-dichloroisocoumarin | - |
Homo sapiens |  |
| 3.4.14.4 | EDTA | - |
Homo sapiens | |
| 3.4.14.4 | p-chloromercuriphenylsulfonic acid | - |
Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.14.4 | 0.3 | - |
Arg-Arg-2-naphthylamide | - |
Homo sapiens | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.14.4 | Zn2+ | contains 1 mol of Zn2+ per mol of enzyme | Homo sapiens | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.14.4 | 93000 | - |
gel filtration | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.14.4 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.14.4 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.14.4 | placenta | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.14.4 | 14.2 | - |
- |
Homo sapiens |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 3.4.14.4 | -20°C, 50% glycerol, 1 year | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.14.4 | Arg-Arg-2-naphthylamide + H2O | - |
Homo sapiens | Arg-Arg + 2-naphthylamine | - |
? | |
| 3.4.14.4 | Lys-Ala-2-naphthylamide + H2O | - |
Homo sapiens | Lys-Ala + 2-naphthylamine | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.14.4 | monomer | 1 * ?, SDS-PAGE | Homo sapiens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.14.4 | 8.8 | - |
- |
Homo sapiens |
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Release 2023.1 (January 2023)
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