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Inhibitors of 2,3-oxidosqualene lanosterol-cyclase as potential antifungal agents

Jolidon, S.; Polak, A.M.; Guerry, P.; Hartman, P.G.; Biochem. Soc. Trans. 18, 47-48 (1990)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
5.4.99.7
19-Azasqualene
-
Candida albicans
5.4.99.7
19-Azasqualene
-
Rattus norvegicus
5.4.99.7
Iminosqualene
-
Candida albicans
5.4.99.7
Iminosqualene
-
Rattus norvegicus
5.4.99.7
additional information
antifungal activity of lanosterol synthase inhibitors
Candida albicans
5.4.99.7
additional information
-
Rattus norvegicus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.4.99.7
Candida albicans
-
-
-
5.4.99.7
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.4.99.7
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.4.99.7
(S)-squalene-2,3-epoxide
-
3610
Rattus norvegicus
Lanosterol
-
3610
Rattus norvegicus
-
5.4.99.7
(S)-squalene-2,3-epoxide
-
3610
Candida albicans
Lanosterol
-
3610
Candida albicans
-
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
5.4.99.7
19-Azasqualene
-
Candida albicans
5.4.99.7
19-Azasqualene
-
Rattus norvegicus
5.4.99.7
Iminosqualene
-
Candida albicans
5.4.99.7
Iminosqualene
-
Rattus norvegicus
5.4.99.7
additional information
antifungal activity of lanosterol synthase inhibitors
Candida albicans
5.4.99.7
additional information
-
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.4.99.7
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.4.99.7
(S)-squalene-2,3-epoxide
-
3610
Rattus norvegicus
Lanosterol
-
3610
Rattus norvegicus
-
5.4.99.7
(S)-squalene-2,3-epoxide
-
3610
Candida albicans
Lanosterol
-
3610
Candida albicans
-