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Literature summary extracted from

  • Hooper, N.M.; Hryszko, J.; Turner, A.J.
    Purification and characterization of pig kidney aminopeptidase P. A glycosyl-phosphatidylinositol-anchored ectoenzyme (1990), Biochem. J., 267, 509-515.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.9 1,10-phenanthroline
-
 Sus scrofa
3.4.11.9 2-mercaptoethanol
-
 Sus scrofa
3.4.11.9 4-chloromercuriphenyl sulfonic acid
-
 Sus scrofa
3.4.11.9 4-hydroxymercuribenzenesulfonate
-
 Sus scrofa
3.4.11.9 4-hydroxymercuribenzoate
-
 Sus scrofa
3.4.11.9 bestatin
-
 Sus scrofa
3.4.11.9 Cu2+ 0.04-4.0 mM 4CuCl2 Sus scrofa
3.4.11.9 dithiothreitol
-
 Sus scrofa
3.4.11.9 EDTA
-
 Sus scrofa
3.4.11.9 EGTA
-
 Sus scrofa
3.4.11.9 Mn2+ above 4 mM Sus scrofa
3.4.11.9 Ni2+ 0.04-4.0 mM NiCl2 Sus scrofa
3.4.11.9 Zn2+ 0.04-4.0 mM ZnCl2 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.9 Co2+ stimulates Sus scrofa
3.4.11.9 Mn2+ stimulates, optimal activity at 4 mM Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.9 91000
-
 x * 91000, reducing conditions, SDS-PAGE Sus scrofa
3.4.11.9 280000
-
 gel filtration Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.9 Sus scrofa
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.11.9 side-chain modification glycoprotein, contains up to 25% of N-linked sugar Sus scrofa

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.9
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.9 kidney cortex Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.11.9 3534
-
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.9 Gly-Pro-4-methylcoumarin 7-amide + H2O
-
 Sus scrofa Gly + Pro-4-methylcoumarin 7-amide
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.11.9 ? x * 91000, reducing conditions, SDS-PAGE Sus scrofa
3.4.11.9 ? non-reducing conditions, SDS-PAGE Sus scrofa