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Literature summary extracted from
- Purification and characterization of two aminopeptidases from guinea-pig small-intestinal mucosa. Cavian intestinal tripeptide hydrolases (1985), Eur. J. Biochem., 146, 429-435.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 3.4.11.4 | bovine serum albumin stabilizes | Cavia porcellus |
| 3.4.11.4 | very unstable during purification | Cavia porcellus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.4 | 1,10-phenanthroline | - |
Cavia porcellus |  |
| 3.4.11.4 | bestatin | - |
Cavia porcellus | |
| 3.4.11.4 | Co2+ | - |
Cavia porcellus | |
| 3.4.11.4 | Cu2+ | - |
Cavia porcellus | |
| 3.4.11.4 | molybdate | - |
Cavia porcellus | |
| 3.4.11.4 | O3-tertiary-butyl-threonylphenylalanylproline | - |
Cavia porcellus | |
| 3.4.11.4 | p-hydroxymercuribenzoate | - |
Cavia porcellus | |
| 3.4.11.4 | Zn2+ | - |
Cavia porcellus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.11.4 | additional information | - |
additional information | - |
Cavia porcellus |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.4 | additional information | no metalloenzyme | Cavia porcellus |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.4 | 68000 | - |
gel filtration | Cavia porcellus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.11.4 | Cavia porcellus | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.11.4 | no modification | no glycoprotein | Cavia porcellus |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.11.4 | peptidases a and b | Cavia porcellus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.11.4 | small intestine mucosa | - |
Cavia porcellus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.4 | additional information | - |
- |
Cavia porcellus |
| 3.4.11.4 | 22.9 | - |
- |
Cavia porcellus |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 3.4.11.4 | -20°C, bovine serum albumin, 5 mg/ml, 6 months | Cavia porcellus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.4 | L-Met-L-Met-L-Met + H2O | - |
Cavia porcellus | L-Met + L-Met-L-Met | - |
? | |
| 3.4.11.4 | L-Phe-Gly-Gly + H2O | - |
Cavia porcellus | L-Phe + Gly-Gly | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.11.4 | monomer | 1 * 65000-80000, SDS-PAGE with reducing agents | Cavia porcellus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.4 | 30 | - |
assay at | Cavia porcellus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.4 | 7.6 | - |
- |
Cavia porcellus |
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