Any feedback?
Literature summary extracted from
- Evidence that the fourth ligand to the [2Fe-2S] cluster in animal ferrochelatase is a cysteine. Characterization of the enzyme from Drosophila melanogaster (1998), J. Biol. Chem., 273, 22311-22316.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.98.1.1 | mitochondrion | - |
Drosophila melanogaster | 5739 | - |
| 4.98.1.1 | mitochondrion | - |
Homo sapiens | 5739 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.98.1.1 | [2Fe-2S]cluster | - |
Drosophila melanogaster |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.98.1.1 | protoporphyrin IX + Fe2+ | Drosophila melanogaster | final step of heme biosynthesis | ? | - |
? | |
| 4.98.1.1 | protoporphyrin IX + Fe2+ | Homo sapiens | final step of heme biosynthesis | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.98.1.1 | Drosophila melanogaster | - |
- |
- |
| 4.98.1.1 | Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.98.1.1 | protoporphyrin + Fe2+ | - |
Drosophila melanogaster | protoheme + 2 H+ | - |
? | |
| 4.98.1.1 | protoporphyrin + Fe2+ | - |
Homo sapiens | protoheme + 2 H+ | - |
? | |
| 4.98.1.1 | protoporphyrin IX + Fe2+ | final step of heme biosynthesis | Drosophila melanogaster | ? | - |
? | |
| 4.98.1.1 | protoporphyrin IX + Fe2+ | final step of heme biosynthesis | Homo sapiens | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
