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Literature summary extracted from
- Ferrochelatase of Rhodopseudomonas spheroides (1970), Biochem. J., 119, 453-462.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.98.1.1 | Cd2+ | - |
Cereibacter sphaeroides |  |
| 4.98.1.1 | Mg2+-protoporphyrin | - |
Cereibacter sphaeroides | |
| 4.98.1.1 | protohaem | - |
Cereibacter sphaeroides |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.98.1.1 | 0.00613 | - |
Co2+ | - |
Cereibacter sphaeroides | |
| 4.98.1.1 | 0.0213 | - |
deuteroporphyrin | - |
Cereibacter sphaeroides | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.98.1.1 | additional information | distribution in guinea pig liver cells: 25% in mitochondria, 35% in peroxisomes and 35% in microsomes, in rat predominantly in microsomes and peroxisomes | Cereibacter sphaeroides | - |
- |
| 4.98.1.1 | soluble | - |
Cereibacter sphaeroides | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.98.1.1 | Cereibacter sphaeroides | - |
2 forms: soluble and particulate | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.98.1.1 | deuteroporphyrin + Fe2+ | - |
Cereibacter sphaeroides | deuteroheme + 2 H+ | - |
? | |
| 4.98.1.1 | Fe2+-hematoporphyrin | - |
Cereibacter sphaeroides | ? | - |
? | |
| 4.98.1.1 | porphyrin + metal ion | Co2+, Fe2+, Zn2+, Ni2+ or Mn2+ | Cereibacter sphaeroides | metalloporphyrin | - |
? | |
| 4.98.1.1 | protoporphyrin + Fe2+ | - |
Cereibacter sphaeroides | protoheme + 2 H+ | - |
? | |
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Release 2023.1 (January 2023)
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