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Literature summary extracted from

  • Inoue, K.; Nishimukai, H.; Yamasawa, K.
    Purification and partial characterization of aldehyde dehydrogenase from human erythrocytes (1979), Biochim. Biophys. Acta, 569, 117-123.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.3 Chloral hydrate competitive with aldehyde Homo sapiens
1.2.1.3 Disulfiram non-competitive Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.3 0.00055
-
 cinnamaldehyde
-
 Homo sapiens
1.2.1.3 0.00065
-
 benzaldehyde
-
 Homo sapiens
1.2.1.3 0.015
-
 NAD+
-
 Homo sapiens
1.2.1.3 0.017
-
 acetylaldehyde at substrate concentrations 0-0.07 mM Homo sapiens
1.2.1.3 0.18
-
 glycolaldehyde
-
 Homo sapiens
1.2.1.3 0.205
-
 glyceraldehyde
-
 Homo sapiens
1.2.1.3 0.765
-
 propanal at substrate concentrations 0.8-20 mM Homo sapiens
1.2.1.3 0.83
-
 acetaldehyde at substrate concentrations 0.8-20 mM Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.3 51500
-
 4 * 51500, SDS-PAGE Homo sapiens
1.2.1.3 210000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.3 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.3
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.3 erythrocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.3 0.462
-
-
 Homo sapiens

Storage Stability

EC Number Storage Stability Organism
1.2.1.3 -20°C, 20% glycerol, less than 15% loss of activity per months Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.3 glyceraldehyde + NAD+ + H2O
-
 Homo sapiens glycerate + NADH
-
 ?
1.2.1.3 glycolaldehyde + NAD+ + H2O
-
 Homo sapiens glycolate + NADH
-
 ?

Subunits

EC Number Subunits Comment Organism
1.2.1.3 tetramer 4 * 51500, SDS-PAGE Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.3 additional information very low activity Homo sapiens
1.2.1.3 NAD+
-
 Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.2.1.3 0.17
-
 Chloral hydrate
-
 Homo sapiens