Any feedback?
Literature summary extracted from
- Multiplicity of liver microsomal flavin-containing monooxygenase in the guinea pig: its purification and characterization (1990), Arch. Biochem. Biophys., 280, 305-312.
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.14.13.8 | 54000 | - |
SDS-PAGE, FMO-I | Cavia porcellus |
| 1.14.13.8 | 56000 | - |
SDS-PAGE, FMO-II | Cavia porcellus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.13.8 | Cavia porcellus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.14.13.8 | 2 forms: FMO-I and FMO-II | Cavia porcellus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.13.8 | liver | - |
Cavia porcellus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.14.13.8 | 0.41 | - |
thiobenzamide S-oxidase activity, FMO-II | Cavia porcellus |
| 1.14.13.8 | 0.436 | - |
thiobenzamide S-oxidase activity, FMO-I | Cavia porcellus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.13.8 | chlorpromazine + NADPH + O2 | - |
Cavia porcellus | ? | - |
? |  |
| 1.14.13.8 | cysteamine + NADPH + O2 | - |
Cavia porcellus | ? | - |
? | |
| 1.14.13.8 | methamphetamine + NADPH + O2 | - |
Cavia porcellus | ? | - |
? | |
| 1.14.13.8 | methimazole + NADPH + O2 | - |
Cavia porcellus | N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O | - |
? | |
| 1.14.13.8 | additional information | specificity of FMO-I and FMO-II | Cavia porcellus | ? | - |
? | |
| 1.14.13.8 | N,N-dimethylaniline + NADPH + O2 | - |
Cavia porcellus | N,N-dimethylaniline N-oxide + NADP+ + H2O | - |
? | |
| 1.14.13.8 | phenylthiourea + NADPH + O2 | - |
Cavia porcellus | ? | - |
? | |
| 1.14.13.8 | thiourea + NADPH + O2 | - |
Cavia porcellus | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.14.13.8 | ? | x * 56000, FMO-II, SDS-PAGE | Cavia porcellus |
| 1.14.13.8 | ? | x * 54000, FMO-I, SDS-PAGE | Cavia porcellus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.13.8 | FAD | flavoprotein | Cavia porcellus | |
| 1.14.13.8 | FAD | 1 FAD per enzyme | Cavia porcellus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
