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Literature summary extracted from

  • Gilbert, H.J.; Drabble, W.T.
    Active-site modification of native and mutant forms of inosine 5-monophosphate dehydrogenase from Escherichia coli K12 (1980), Biochem. J., 191, 533-541.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.205 5,5'-dithiobis(2-nitrobenzoate)
-
 Escherichia coli
1.1.1.205 6-Chloro-9-beta-D-ribofuranosylpurine 5 '-phosphate covalent modification of the enzyme, total inactivation after 15 min at 0.01 mg/ml Cl-IMP, activity can be restored with 2-mercaptoethanol Escherichia coli
1.1.1.205 iodoacetamide
-
 Escherichia coli
1.1.1.205 iodoacetate
-
 Escherichia coli
1.1.1.205 methyl methanethiosulfonate
-
 Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.205 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.205
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.205 inosine 5'-phosphate + NAD+ + H2O
-
 Escherichia coli xanthosine 5'-phosphate + NADH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.205 NAD+
-
 Escherichia coli