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Literature summary extracted from

  • Nakayama, T.; Yashiro, K.; Inoue, Y.; Matsuura, K.; Ichikawa, H.; Hara, A.; Sawada, H.
    Characterization of pulmonary carbonyl reductase of mouse and guinea pig (1986), Biochim. Biophys. Acta, 882, 220-227.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.184 2-mercaptoethanol
-
 Mus musculus
1.1.1.184 dithiothreitol
-
 Cavia porcellus
1.1.1.184 dithiothreitol
-
 Mus musculus
1.1.1.184 FeSO4
-
 Cavia porcellus
1.1.1.184 FeSO4
-
 Mus musculus
1.1.1.184 Isobutyramide
-
 Mus musculus
1.1.1.184 pyrazole
-
 Cavia porcellus
1.1.1.184 pyrazole
-
 Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.184 additional information
-
 additional information
-
 Cavia porcellus
1.1.1.184 additional information
-
 additional information
-
 Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.184 23000
-
 4 * 23000, mouse, SDS-PAGE Mus musculus
1.1.1.184 90000
-
 gel filtration Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.184 Cavia porcellus
-
-
-
1.1.1.184 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.184
-
 Cavia porcellus
1.1.1.184
-
 Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.184 lung
-
 Cavia porcellus
-
1.1.1.184 lung
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.184 additional information
-
-
 Cavia porcellus
1.1.1.184 additional information
-
-
 Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.184 4-nitroacetophenone + NADPH
-
 Cavia porcellus ?
-
 ?
1.1.1.184 additional information overview Cavia porcellus ?
-
 ?
1.1.1.184 additional information overview Mus musculus ?
-
 ?
1.1.1.184 additional information NADH also acts as cofactor Cavia porcellus ?
-
 ?
1.1.1.184 additional information NADH also acts as cofactor Mus musculus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.1.184 tetramer
-
 Cavia porcellus
1.1.1.184 tetramer 4 * 23000, mouse, SDS-PAGE Mus musculus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.184 25
-
 assay at Cavia porcellus
1.1.1.184 25
-
 assay at Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.184 5 6 NADH + 4-nitroacetophenone Mus musculus
1.1.1.184 5.2
-
 NADPH + 4-nitroacetophenone Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.184 NADPH
-
 Cavia porcellus
1.1.1.184 NADPH
-
 Mus musculus