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Literature summary extracted from

  • Gentry-Weeks, C.R.; Spokes, J.; Thompson, J.
    beta-Cystathionase from Bordetella avium. Role(s) of lysine 214 and cysteine residues in activity and cytotoxicity (1995), J. Biol. Chem., 270, 7695-7702.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
4.4.1.13 C117G inactive protein, pyridoxal 5'-phosphate is not detectable in the mutant protein, enhanced susceptibility to chymotrypsin digestion Bordetella avium
4.4.1.13 C279 activity is comparable with that of the native enzyme Bordetella avium
4.4.1.13 C309A inactive protein, pyridoxal 5'-phosphate is not detectable in the mutant protein, enhanced susceptibility to chymotrypsin digestion Bordetella avium
4.4.1.13 C88A activity is comparable with that of the native enzyme Bordetella avium

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.13 NEM
-
 Bordetella avium

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.13 Bordetella avium
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.13 L-cystathionine + H2O
-
 Bordetella avium L-homocysteine + NH3 + pyruvate
-
 ?
4.4.1.13 L-cystine + H2O
-
 Bordetella avium L-thiocysteine + pyruvate + NH3
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.13 pyridoxal 5'-phosphate
-
 Bordetella avium