Any feedback?
Literature summary extracted from
- Conversion of aldonic acids to their corresponding 2-keto-3-deoxy-analogs by the non-carbohydrate enzyme dihydroxy acid dehydratase (DHAD) (1995), Bioorg. Med. Chem., 3, 487-494.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.9 | 2,4,5,6-tetrahydroxyhexanoate | - |
Spinacia oleracea |  |
| 4.2.1.9 | 2,4,5-trihydroxypentanoate | - |
Spinacia oleracea | |
| 4.2.1.9 | 2,4-dihydroxybutanoate | - |
Spinacia oleracea | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.2.1.9 | 0.65 | - |
L-threonate | - |
Spinacia oleracea | |
| 4.2.1.9 | 1.75 | - |
D-erythronate | - |
Spinacia oleracea | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.9 | 2,3-dihydroxy-3-methylpentanoate | Spinacia oleracea | involved in synthesis of Ile | ? | - |
? | |
| 4.2.1.9 | 2,3-dihydroxyisovalerate | Spinacia oleracea | involved in biosynthesis of Val | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.9 | Spinacia oleracea | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.2.1.9 | - |
Spinacia oleracea |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.2.1.9 | leaf | - |
Spinacia oleracea | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.9 | 0.132 | - |
- |
Spinacia oleracea |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.9 | 2,3-dihydroxy-3-methylbutanoate | - |
Spinacia oleracea | 2-oxoisovalerate + H2O | - |
? | |
| 4.2.1.9 | 2,3-dihydroxy-3-methylpentanoate | - |
Spinacia oleracea | 3-methyl-2-oxopentanoate + H2O | - |
? | |
| 4.2.1.9 | 2,3-dihydroxy-3-methylpentanoate | involved in synthesis of Ile | Spinacia oleracea | ? | - |
? | |
| 4.2.1.9 | 2,3-dihydroxyisovalerate | involved in biosynthesis of Val | Spinacia oleracea | ? | - |
? | |
| 4.2.1.9 | D-erythronate | - |
Spinacia oleracea | ? | - |
? | |
| 4.2.1.9 | L-threonate | - |
Spinacia oleracea | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
