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Literature summary extracted from

  • Frey, P.A.; Ballinger, M.D.; Reed, G.H.
    S-Adenosylmethionine: a "poor man's coenzyme B12" in the reaction of lysine 2,3-aminomutase (1998), Biochem. Soc. Trans., 26, 304-310.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.4.3.2 S-adenosylmethionine required Clostridium sp.
5.4.3.2 S-adenosylmethionine plays a role in lysine 2,3-aminomutase reaction Clostridium sp.

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
5.4.3.2 Fe2+ Fe-S cluster is required as cofactor Clostridium sp.
5.4.3.2 Fe2+ contains [4Fe-4S] clusters Clostridium sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.3.2 L-Lys Clostridium sp. production of (3S)-3,6-diaminohexanoic acid for the biosynthesis of antibiotics ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.4.3.2 Clostridium sp.
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
5.4.3.2 L-lysine = (3S)-3,6-diaminohexanoate mechanism of radical rearrangement in the reaction Clostridium sp.
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.3.2 L-Lys
-
 Clostridium sp. (3S)-3,6-diaminohexanoic acid
-
 ?
5.4.3.2 L-Lys production of (3S)-3,6-diaminohexanoic acid for the biosynthesis of antibiotics Clostridium sp. ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
5.4.3.2 pyridoxal 5'-phosphate required Clostridium sp.
5.4.3.2 pyridoxal 5'-phosphate role in lysine 2,3-aminomutase reaction Clostridium sp.