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Literature summary extracted from

  • Sancar , G.B.; Sancar, A.
    Structure and function of DNA photolyases (1987), Trends Biochem. Sci., 12, 259-261.
No PubMed abstract available

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.99.3 49000
-
-
 Escherichia coli
4.1.99.3 49000
-
-
 Streptomyces griseus
4.1.99.3 53990
-
-
 Escherichia coli
4.1.99.3 53994
-
 1 * 53994 Escherichia coli
4.1.99.3 66189
-
 1 * 66189 Saccharomyces cerevisiae
4.1.99.3 66190
-
-
 Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.99.3 cyclobutadipyrimidine in DNA Escherichia coli the enzyme converts the energy of light of near UV to visible wavelengths into chemical energy to break the cyclobutane ring of pyrimidine dimers in DNA and thus prevents the lethal and mutagenic effects of far UV, 200-300 nm ?
-
 ?
4.1.99.3 cyclobutadipyrimidine in DNA Saccharomyces cerevisiae the enzyme converts the energy of light of near UV to visible wavelengths into chemical energy to break the cyclobutane ring of pyrimidine dimers in DNA and thus prevents the lethal and mutagenic effects of far UV, 200-300 nm ?
-
 ?
4.1.99.3 cyclobutadipyrimidine in DNA Streptomyces griseus the enzyme converts the energy of light of near UV to visible wavelengths into chemical energy to break the cyclobutane ring of pyrimidine dimers in DNA and thus prevents the lethal and mutagenic effects of far UV, 200-300 nm ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.99.3 Escherichia coli
-
-
-
4.1.99.3 Saccharomyces cerevisiae
-
-
-
4.1.99.3 Streptomyces griseus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.99.3 cyclobutadipyrimidine in DNA
-
 Escherichia coli pyrimidine residues in DNA
-
 ?
4.1.99.3 cyclobutadipyrimidine in DNA
-
 Saccharomyces cerevisiae pyrimidine residues in DNA
-
 ?
4.1.99.3 cyclobutadipyrimidine in DNA
-
 Streptomyces griseus pyrimidine residues in DNA
-
 ?
4.1.99.3 cyclobutadipyrimidine in DNA the enzyme converts the energy of light of near UV to visible wavelengths into chemical energy to break the cyclobutane ring of pyrimidine dimers in DNA and thus prevents the lethal and mutagenic effects of far UV, 200-300 nm Escherichia coli ?
-
 ?
4.1.99.3 cyclobutadipyrimidine in DNA the enzyme converts the energy of light of near UV to visible wavelengths into chemical energy to break the cyclobutane ring of pyrimidine dimers in DNA and thus prevents the lethal and mutagenic effects of far UV, 200-300 nm Saccharomyces cerevisiae ?
-
 ?
4.1.99.3 cyclobutadipyrimidine in DNA the enzyme converts the energy of light of near UV to visible wavelengths into chemical energy to break the cyclobutane ring of pyrimidine dimers in DNA and thus prevents the lethal and mutagenic effects of far UV, 200-300 nm Streptomyces griseus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.99.3 monomer 1 * 49000 Streptomyces griseus
4.1.99.3 monomer 1 * 66189 Saccharomyces cerevisiae
4.1.99.3 monomer 1 * 53994 Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.99.3 5-deazaflavin cofactor Streptomyces griseus
4.1.99.3 FADH2 FADH2 cofactor Escherichia coli
4.1.99.3 FADH2 FADH2 cofactor Saccharomyces cerevisiae
4.1.99.3 FADH2 FADH2 cofactor Streptomyces griseus
4.1.99.3 pterin cofactor Escherichia coli
4.1.99.3 pterin cofactor Saccharomyces cerevisiae