EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.1.3.27 | 2-oxoglutarate | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | Bromopyruvate | inactivation prevented by chorismate and Trp | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | Diethylamine | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | Dimethylamine | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | Gln | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | Glu | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | L-Trp | competitive with chorismate, noncompetitive with NH4+, reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | methylamine | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | N-Methylhydroxylamine | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | NEM | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | PCMB | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | pyruvate | competitive with respect to chorismate, noncompetitive with respect to NH4+, reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | trimethylamine | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.1.3.27 | 0.11 | - |
chorismate | reaction of component I, with NH4+ as cosubstrate | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | 24 | - |
NH4+ | reaction of component I | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.1.3.27 | Mg2+ | required | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.1.3.27 | Mg2+ | reaction of component I with NH4+ as substrate | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.3.27 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.1.3.27 | component I | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.1.3.27 | 0.384 | - |
activity of component I | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.3.27 | chorismate + L-Gln | component I is inactive with L-Gln | Salmonella enterica subsp. enterica serovar Typhimurium | anthranilate + pyruvate + L-glutamate | - |
? | |
4.1.3.27 | chorismate + NH4+ | reaction is catalyzed by component I alone and in combination with component II | Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.1.3.27 | More | component I has a MW of 63000 Da, gel filtration | Salmonella enterica subsp. enterica serovar Typhimurium |