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Literature summary extracted from

  • Liang, P.H.; Yang, G.; Dunaway-Mariano, D.
    Specificity of 4-chlorobenzoyl coenzyme A dehalogenase catalyzed dehalogenation of halogenated aromatics (1993), Biochemistry, 32, 12245-12250.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.8.1.7
-
 Pseudomonas sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.8.1.7 4-Chlorobenzoate
-
 Pseudomonas sp.
3.8.1.7 benzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 CoA
-
 Pseudomonas sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.8.1.7 0.0037
-
 4-chlorobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 0.0042
-
 4-bromobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 0.0055
-
 4-chloro-3-nitrobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 0.0065
-
 4-iodobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 0.0104
-
 2,4-dichlorobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 0.03
-
 4-chloro-2-nitrobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 0.042
-
 3,4-dichlorobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 0.075
-
 4-chloro-3-methylbenzoyl-CoA
-
 Pseudomonas sp.

Organism

EC Number Organism UniProt Comment Textmining
3.8.1.7 Pseudomonas sp.
-
-
-
3.8.1.7 Pseudomonas sp.
-
 recombinant enzyme expressed in Escherichia coli
-
3.8.1.7 Pseudomonas sp. CBS-3
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.8.1.7 2,4-dichlorobenzoyl-CoA + H2O
-
 Pseudomonas sp. ?
-
 ?
3.8.1.7 2,4-dichlorobenzoyl-CoA + H2O
-
 Pseudomonas sp. CBS-3 ?
-
 ?
3.8.1.7 3,4-dichlorobenzoyl-CoA + H2O
-
 Pseudomonas sp. ?
-
 ?
3.8.1.7 3,4-dichlorobenzoyl-CoA + H2O
-
 Pseudomonas sp. CBS-3 ?
-
 ?
3.8.1.7 4-bromobenzoyl-CoA + H2O
-
 Pseudomonas sp. 4-hydroxybenzoyl-CoA + bromide
-
 ?
3.8.1.7 4-bromobenzoyl-CoA + H2O
-
 Pseudomonas sp. CBS-3 4-hydroxybenzoyl-CoA + bromide
-
 ?
3.8.1.7 4-chloro-2-nitrobenzoyl-CoA + H2O
-
 Pseudomonas sp. ?
-
 ?
3.8.1.7 4-chloro-3-methylbenzoyl-CoA + H2O
-
 Pseudomonas sp. ?
-
 ?
3.8.1.7 4-chloro-3-nitrobenzoyl-CoA + H2O
-
 Pseudomonas sp. ?
-
 ?
3.8.1.7 4-chlorobenzoyl-CoA + H2O
-
 Pseudomonas sp. 4-hydroxybenzoyl-CoA + chloride
-
 ?
3.8.1.7 4-chlorobenzoyl-CoA + H2O
-
 Pseudomonas sp. CBS-3 4-hydroxybenzoyl-CoA + chloride
-
 ?
3.8.1.7 4-chlorobenzoyl-CoA + H2O
-
 Pseudomonas sp. 4-hydroxybenzoyl CoA + chloride
-
 ?
3.8.1.7 4-iodobenzoyl-CoA + H2O
-
 Pseudomonas sp. 4-hydroxybenzoyl-CoA + iodide
-
 ?
3.8.1.7 4-iodobenzoyl-CoA + H2O
-
 Pseudomonas sp. CBS-3 4-hydroxybenzoyl-CoA + iodide
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.8.1.7 0.052
-
 3,4-dichlorobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 0.063
-
 4-chloro-2-nitrobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 0.511
-
 2,4-dichlorobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 0.6
-
 4-chlorobenzoyl-CoA multiple turnovers Pseudomonas sp.
3.8.1.7 1.1
-
 4-iodobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 1.4
-
 4-bromobenzoyl-CoA
-
 Pseudomonas sp.
3.8.1.7 2
-
 4-chlorobenzoyl-CoA single turnover Pseudomonas sp.