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Literature summary extracted from

  • Roth, J.R.; Lawrence, J.G.; Rubenfield, M.; Kieffer-Higgins, S.; Church, G.M.
    Characterization of the cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium (1993), J. Bacteriol., 175, 3303-3316.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.130 S-adenosyl-L-methionine + precorrin-2 Salmonella enterica subsp. enterica serovar Typhimurium one enzyme of the cobalamin biosynthetic pathway ?
-
 ?
2.1.1.130 S-adenosyl-L-methionine + precorrin-2 Pseudomonas denitrificans (nom. rej.) one enzyme of the cobalamin biosynthetic pathway ?
-
 ?
2.1.1.132 Adenosyl-L-methionine + precorrin-6Y Salmonella enterica subsp. enterica serovar Typhimurium enzyme of the cobalamin biosynthetic pathway ?
-
 ?
2.1.1.132 Adenosyl-L-methionine + precorrin-6Y Pseudomonas denitrificans (nom. rej.) enzyme of the cobalamin biosynthetic pathway ?
-
 ?
5.4.99.60 Precorrin-8X Salmonella enterica subsp. enterica serovar Typhimurium the enzyme is involved in the cobalamin biosynthetic pathway ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.130 Pseudomonas denitrificans (nom. rej.)
-
-
-
2.1.1.130 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
2.1.1.132 Pseudomonas denitrificans (nom. rej.)
-
-
-
2.1.1.132 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
5.4.99.60 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.130 S-adenosyl-L-methionine + precorrin-2
-
 Salmonella enterica subsp. enterica serovar Typhimurium S-adenosyl-L-homocysteine + precorrin-3A
-
 ?
2.1.1.130 S-adenosyl-L-methionine + precorrin-2
-
 Pseudomonas denitrificans (nom. rej.) S-adenosyl-L-homocysteine + precorrin-3A
-
 ?
2.1.1.130 S-adenosyl-L-methionine + precorrin-2 one enzyme of the cobalamin biosynthetic pathway Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
2.1.1.130 S-adenosyl-L-methionine + precorrin-2 one enzyme of the cobalamin biosynthetic pathway Pseudomonas denitrificans (nom. rej.) ?
-
 ?
2.1.1.132 Adenosyl-L-methionine + precorrin-6Y enzyme of the cobalamin biosynthetic pathway Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
2.1.1.132 Adenosyl-L-methionine + precorrin-6Y enzyme of the cobalamin biosynthetic pathway Pseudomonas denitrificans (nom. rej.) ?
-
 ?
5.4.99.60 Precorrin-8X
-
 Salmonella enterica subsp. enterica serovar Typhimurium Hydrogenobyrinate
-
 ?
5.4.99.60 Precorrin-8X the enzyme is involved in the cobalamin biosynthetic pathway Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?