Literature summary extracted from

Soler, D.; Nomizu, T.; Brown, W.E.; Chen, M.; Ye, Q.Z.; van Wart, H.E.; Auld, D.S.
Zinc content of promatrilysin, matrilysin and the stromelysin catalytic domain (1994), Biochem. Biophys. Res. Commun., 201, 917-923.

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
3.4.24.23	additional information	promatrilysin and matrilysin do not contain significant amounts of Fe, Cu, Mn, or Ni	Mammalia
3.4.24.23	Zinc	two metal binding sites at which zinc is bound firmly and possibly a third site at which it is bound weakly	Mammalia
3.4.24.23	Zinc	2.36 (promatrilysin expressed in Escherichia coli), 2.13 (promatrilysin expressed in Chinese hamster ovary cells)	Mammalia
3.4.24.23	Zinc	2.22 (activated enzyme)	Mammalia

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.23	Mammalia	-	expression in Escherichia coli and Chinese hamster ovary cells, expression vector pGEX-2T	-

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Release 2026.1 (March 2026)