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Literature summary extracted from
- Chemical modification of essential residues in purified rat liver protein disulphide-isomerase (1984), Biochem. Soc. Trans., 12, 1042.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.4.1 | 4,4'-diisothiocyano-2,2'-stilbene disulfonic acid | considerably more effective after preincubation with DTT | Rattus norvegicus |  |
| 5.3.4.1 | Diazobenzene sulfonic acid | considerably more effective after preincubation with DTT | Rattus norvegicus | |
| 5.3.4.1 | iodoacetamide | incubation after pretreatment with DTT or GSH | Rattus norvegicus | |
| 5.3.4.1 | N-Iodoacetyl-N'-(5-sulfo)-1-naphthyl-diaminoethane | incubation after pretreatment with DTT or GSH | Rattus norvegicus | |
| 5.3.4.1 | NEM | incubation after pretreatment with DTT or GSH | Rattus norvegicus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.4.1 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.3.4.1 | liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.4.1 | Proteins | native, reduced or with wrong disulfide bonds | Rattus norvegicus | Proteins | with correct disulfide bonds | ? | |
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Release 2023.1 (January 2023)
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