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Literature summary extracted from

  • Rouille, Y.; Westermark, G.; Martin, S.K.; Steiner, D.F.
    Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells (1994), Proc. Natl. Acad. Sci. USA, 91, 3242-3246.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.94 additional information Mammalia present on secretory pathway of neuroendocrine cells ?
-
 ?
3.4.21.94 Proglucagon + H2O Mammalia key endoprotease responsible for proglucagon processing in cells with the alpha-cell phenotype ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.94 Mammalia
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.94 pancreatic alpha cell normal and alphaTC1-6 Mammalia
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.94 additional information present on secretory pathway of neuroendocrine cells Mammalia ?
-
 ?
3.4.21.94 Proglucagon + H2O dibasic cleavage sites Mammalia Glucagon + ?
-
 ?
3.4.21.94 Proglucagon + H2O key endoprotease responsible for proglucagon processing in cells with the alpha-cell phenotype Mammalia ?
-
 ?