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Literature summary extracted from

  • Seidah, N.G.; Day, R.; Chretien, M.
    The family of pro-hormone and pro-protein convertases (1993), Biochem. Soc. Trans., 21, 685-691.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.75 Mammalia
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3.4.21.75 Rattus norvegicus
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Synonyms

EC Number Synonyms Comment Organism
3.4.21.75 additional information one of a group of subtilisin homologues structurally and functionally similar to kexin Rattus norvegicus
3.4.21.75 additional information one of a group of subtilisin homologues structurally and functionally similar to kexin Mammalia
3.4.21.75 additional information at least 3 related enzymes are recognized in mammals: PC2, PC3, identical with PC1and PC4, which have somewhat different specificities, the integral membrane protein furin may be of ancient origin, possibly ancestral to the secretory granule processing enzymes lacking transmembrane domains, such as PC2 and PC3 Rattus norvegicus
3.4.21.75 additional information at least 3 related enzymes are recognized in mammals: PC2, PC3, identical with PC1and PC4, which have somewhat different specificities, the integral membrane protein furin may be of ancient origin, possibly ancestral to the secretory granule processing enzymes lacking transmembrane domains, such as PC2 and PC3 Mammalia