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Literature summary extracted from

  • Drysdale, M.J.; Reinhard, J.F.
    S-aryl cysteine S,S-dioxides as inhibitors of mammalian kynureninase (1998), Bioorg. Med. Chem. Lett., 8, 133-138.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.7.1.3 2-amino-3-fluoro-S-phenyl cysteine S,S-dioxide
-
 Rattus norvegicus
3.7.1.3 2-amino-3-methoxy-S-phenyl cysteine S,S-dioxide
-
 Rattus norvegicus
3.7.1.3 2-amino-5-methyl-S-phenyl cysteine S,S-dioxide
-
 Rattus norvegicus
3.7.1.3 2-amino-S-phenyl cysteine S,S-dioxide
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.7.1.3 3-hydroxy-L-kynurenine + H2O Rattus norvegicus
-
 3-hydroxyanthranilate + L-Ala
-
 ?
3.7.1.3 L-kynurenine + H2O Rattus norvegicus
-
 anthranilate + L-alanine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.7.1.3 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.7.1.3 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.7.1.3 3-hydroxy-L-kynurenine + H2O
-
 Rattus norvegicus 3-hydroxyanthranilate + L-alanine
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O
-
 Rattus norvegicus 3-hydroxyanthranilate + L-Ala
-
 ?
3.7.1.3 L-kynurenine + H2O
-
 Rattus norvegicus anthranilate + L-alanine
-
 ?