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Literature summary extracted from

  • Shetty, A.S.; Gaertner, F.H.
    Kynureninase-type enzymes of Penicillium roqueforti, Aspergillus niger, Rhizopus stolonifer, and Pseudomonas fluorescens: Further evidence for distinct kynureninase and hydroxykynureninase activities (1975), J. Bacteriol., 122, 235-244.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
3.7.1.3 medicine tryptophan metabolism Aspergillus niger
3.7.1.3 medicine tryptophan metabolism Pseudomonas fluorescens
3.7.1.3 medicine tryptophan metabolism Penicillium roqueforti
3.7.1.3 medicine tryptophan metabolism Rhizopus stolonifer

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.7.1.3 0.0039
-
 3-hydroxy-L-kynurenine
-
 Aspergillus niger
3.7.1.3 0.0046
-
 3-hydroxy-L-kynurenine
-
 Penicillium roqueforti
3.7.1.3 0.0067
-
 3-hydroxy-L-kynurenine
-
 Rhizopus stolonifer
3.7.1.3 0.01
-
 kynurenine
-
 Penicillium roqueforti
3.7.1.3 0.025
-
 kynurenine
-
 Rhizopus stolonifer
3.7.1.3 0.08
-
 kynurenine
-
 Aspergillus niger

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.7.1.3 3-hydroxy-L-kynurenine + H2O Aspergillus niger
-
 3-hydroxyanthranilate + L-Ala
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O Pseudomonas fluorescens
-
 3-hydroxyanthranilate + L-Ala
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O Penicillium roqueforti
-
 3-hydroxyanthranilate + L-Ala
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O Rhizopus stolonifer
-
 3-hydroxyanthranilate + L-Ala
-
 ?
3.7.1.3 L-kynurenine + H2O Aspergillus niger
-
 anthranilate + L-alanine
-
 ?
3.7.1.3 L-kynurenine + H2O Pseudomonas fluorescens
-
 anthranilate + L-alanine
-
 ?
3.7.1.3 L-kynurenine + H2O Penicillium roqueforti
-
 anthranilate + L-alanine
-
 ?
3.7.1.3 L-kynurenine + H2O Rhizopus stolonifer
-
 anthranilate + L-alanine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.7.1.3 Aspergillus niger
-
-
-
3.7.1.3 Penicillium roqueforti
-
-
-
3.7.1.3 Pseudomonas fluorescens
-
-
-
3.7.1.3 Rhizopus stolonifer
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.7.1.3
-
 Aspergillus niger
3.7.1.3
-
 Pseudomonas fluorescens
3.7.1.3
-
 Penicillium roqueforti
3.7.1.3
-
 Rhizopus stolonifer

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.7.1.3 3-hydroxy-L-kynurenine + H2O
-
 Aspergillus niger 3-hydroxyanthranilate + L-alanine
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O
-
 Pseudomonas fluorescens 3-hydroxyanthranilate + L-alanine
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O
-
 Penicillium roqueforti 3-hydroxyanthranilate + L-alanine
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O
-
 Rhizopus stolonifer 3-hydroxyanthranilate + L-alanine
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O
-
 Aspergillus niger 3-hydroxyanthranilate + L-Ala
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O
-
 Pseudomonas fluorescens 3-hydroxyanthranilate + L-Ala
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O
-
 Penicillium roqueforti 3-hydroxyanthranilate + L-Ala
-
 ?
3.7.1.3 3-hydroxy-L-kynurenine + H2O
-
 Rhizopus stolonifer 3-hydroxyanthranilate + L-Ala
-
 ?
3.7.1.3 L-kynurenine + H2O
-
 Aspergillus niger anthranilate + L-alanine
-
 ?
3.7.1.3 L-kynurenine + H2O
-
 Pseudomonas fluorescens anthranilate + L-alanine
-
 ?
3.7.1.3 L-kynurenine + H2O
-
 Penicillium roqueforti anthranilate + L-alanine
-
 ?
3.7.1.3 L-kynurenine + H2O
-
 Rhizopus stolonifer anthranilate + L-alanine
-
 ?