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Literature summary extracted from

  • Meister, A.; Greenstein, J.P.
    Enzymatic hydrolysis of 2,4-diketo acids (1948), J. Biol. Chem., 175, 573-588.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.7.1.2 Felis catus
-
-
-
3.7.1.2 Mus musculus
-
-
-
3.7.1.2 Oryctolagus cuniculus
-
-
-
3.7.1.2 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.7.1.2
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.7.1.2 kidney
-
 Mus musculus
-
3.7.1.2 kidney
-
 Rattus norvegicus
-
3.7.1.2 kidney
-
 Oryctolagus cuniculus
-
3.7.1.2 kidney
-
 Felis catus
-
3.7.1.2 liver
-
 Mus musculus
-
3.7.1.2 liver
-
 Rattus norvegicus
-
3.7.1.2 liver
-
 Oryctolagus cuniculus
-
3.7.1.2 liver
-
 Felis catus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.7.1.2 0.018
-
 kidney Oryctolagus cuniculus
3.7.1.2 0.025
-
 kidney, 2,4-diketo-6-methyl heptanoate Rattus norvegicus
3.7.1.2 0.026
-
 kidney Felis catus
3.7.1.2 0.027
-
 liver Oryctolagus cuniculus
3.7.1.2 0.036
-
 kidney, 2,4-diketooctanoate Rattus norvegicus
3.7.1.2 0.048
-
 liver, 2,4-diketo-6-methyl heptanoate Rattus norvegicus
3.7.1.2 0.0523
-
 kidney, 2,4-diketoheptanoate Rattus norvegicus
3.7.1.2 0.0547
-
 kidney Rattus norvegicus
3.7.1.2 0.055
-
 liver Felis catus
3.7.1.2 0.0575
-
 kidney Mus musculus
3.7.1.2 0.061
-
 kidney, 2,4-diketo-5,5-dimethyl hexanoate Rattus norvegicus
3.7.1.2 0.0688
-
 liver Rattus norvegicus
3.7.1.2 0.07
-
 liver, 2,4-diketooctanoate Rattus norvegicus
3.7.1.2 0.0803
-
 liver Mus musculus
3.7.1.2 0.0885
-
 kidney, 2,4-diketononanoate Rattus norvegicus
3.7.1.2 0.0923
-
 liver, 2,4-diketoheptanoate Rattus norvegicus
3.7.1.2 0.103
-
 liver, 2,4-diketo-5,5-dimethyl hexanoate Rattus norvegicus
3.7.1.2 0.111
-
 liver, 2,4-diketoundecanoate Rattus norvegicus
3.7.1.2 0.127
-
 kidney, 2,4-diketovalerate Rattus norvegicus
3.7.1.2 0.148
-
 kidney, 2,4-diketo-5-methyl hexanoate Rattus norvegicus
3.7.1.2 0.16
-
 kidney, 2,4-diketocaprate Rattus norvegicus
3.7.1.2 0.168
-
 liver, 2,4-diketononanoate Rattus norvegicus
3.7.1.2 0.245
-
 kidney, 2,4-diketohexanoate Rattus norvegicus
3.7.1.2 0.248
-
 liver, 2,4-diketo-5-methyl hexanoate Rattus norvegicus
3.7.1.2 0.25
-
 liver, 2,4-diketovalerate Rattus norvegicus
3.7.1.2 0.337
-
 liver, 2,4-diketocaprate Rattus norvegicus
3.7.1.2 0.395
-
 liver, 2,4-diketohexanoate Rattus norvegicus
3.7.1.2 0.495
-
 kidney, 2,4-diketoundecanoate Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.7.1.2 2,4-diketo-4-(4-methylphenyl)butyrate + H2O
-
 Rattus norvegicus pyruvate + (4-methylphenyl)acetate
-
 ?
3.7.1.2 2,4-diketo-4-phenylbutyrate + H2O
-
 Rattus norvegicus pyruvate + phenylacetate
-
 ?
3.7.1.2 2,4-diketo-5,5-dimethylhexanoate + H2O
-
 Rattus norvegicus pyruvate + 2,2-dimethylpropanoate
-
 ?
3.7.1.2 2,4-diketo-5-methylheptanoate + H2O
-
 Rattus norvegicus pyruvate + 2-methylbutanoate
-
 ?
3.7.1.2 2,4-diketo-5-methylhexanoate + H2O
-
 Rattus norvegicus pyruvate + isobutanoate
-
 ?
3.7.1.2 2,4-diketocaprate + H2O
-
 Rattus norvegicus pyruvate + heptanoate
-
 ?
3.7.1.2 2,4-diketoheptanoate + H2O
-
 Rattus norvegicus pyruvate + butanoate
-
 ?
3.7.1.2 2,4-diketohexanoate + H2O
-
 Rattus norvegicus pyruvate + propanoate
-
 ?
3.7.1.2 2,4-diketononanoate + H2O
-
 Rattus norvegicus pyruvate + hexanoate
-
 ?
3.7.1.2 2,4-diketooctanoate + H2O
-
 Rattus norvegicus pyruvate + pentanoate
-
 ?
3.7.1.2 2,4-diketoundecanoate + H2O
-
 Rattus norvegicus pyruvate + octanoate
-
 ?
3.7.1.2 2,4-diketovalerate + H2O
-
 Rattus norvegicus pyruvate + acetate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.7.1.2 7.5 7.8 2,4-diketohexanoate Rattus norvegicus
3.7.1.2 8 8.5 2,4-diketocaprate Rattus norvegicus
3.7.1.2 8 8.6 2,4-diketononanoate Rattus norvegicus