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Literature summary extracted from

  • Riva, C.M.; Barra, Y.; Cano, J.P.; Tubiana, N.; Lejeune, C.; Merlin, M.; de Sousa, G.; Carcassonne, Y.; Kreis, W.; Lovecchio, J.; Rottachi, C.; Rustum, Y.M.
    Correlation between deoxycytidine kinase and deaminase activities and response to therapy with ARA-C (1990), J. Cell. Pharmacol., 1, 79-85.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.4.12 arabinosylcytosine ara-C, deactivating dCMP deaminase Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.4.12 dCMP + H2O Homo sapiens
-
dUMP + NH3
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.12 Homo sapiens
-
human
-
3.5.4.12 Homo sapiens
-
patients with acute nonlymphocytic leukemia
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.4.12 CCRF-CEM cell
-
Homo sapiens
-
3.5.4.12 KG-1 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.12 dCMP + H2O
-
Homo sapiens dUMP + NH3
-
?