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Literature summary extracted from

  • Sugie, M.; Suzuki, H.
    Optical resolution of DL-amino acids with D-Aminoacylase of Streptomyces (1980), Agric. Biol. Chem., 44, 1089-1095.
No PubMed abstract available

Application

EC Number Application Comment Organism
3.5.1.14 medicine preparation of commercially important amino acids as components for semisynthetic penicillins and cephalosporins Streptomyces sp.
3.5.1.14 synthesis thermostable enzyme useful for industrial production, optical resolution of DL-amino acids on an industrial scale, utilization in industrial production of stereoisomers from racemates Streptomyces sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.14 AgNO3
-
 Streptomyces sp.
3.5.1.14 HgCl2
-
 Streptomyces sp.
3.5.1.14 iodoacetic acid higher inhibitory effect on L-aminoacylase Streptomyces sp.
3.5.1.14 sodium arsenite higher inhibitory effect on L-aminacylase Streptomyces sp.

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.14 no activity in Streptomyces olivaceus
-
-
-
3.5.1.14 no activity in Streptomyces olivaceus IFO 12805
-
-
-
3.5.1.14 Streptomyces sp.
-
 olivaeus 62 , tuirus
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.14 partially Streptomyces sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.14 N-acetyl-DL-aspartate + H2O
-
 Streptomyces sp. acetate + DL-aspartate
-
 ?
3.5.1.14 N-acetyl-DL-methionine + H2O
-
 Streptomyces sp. DL-methionine + acetate
-
 ?
3.5.1.14 N-acetyl-DL-phenylglycine + H2O only D-isomer hydrolyzed Streptomyces sp. DL-phenylglycine + acetate
-
 ?
3.5.1.14 N-acetyl-DL-tyrosine + H2O prefers D-isomer Streptomyces sp. acetate + DL-tyrosine
-
 ?
3.5.1.14 N-acetyl-L-alanine + H2O
-
 Streptomyces sp. L-alanine + acetate
-
 ?
3.5.1.14 N-acetyl-L-arginine + H2O
-
 Streptomyces sp. acetate + L-arginine
-
 ?
3.5.1.14 N-acetyl-L-phenylalanine + H2O prefers D-isomer Streptomyces sp. L-phenylalanine + acetate
-
 ?
3.5.1.14 N-acetyl-L-valine + H2O
-
 Streptomyces sp. L-valine + acetate
-
 ?
3.5.1.14 N-chloroacetyl-L-leucine + H2O
-
 Streptomyces sp. chloroacetate + L-leucine
-
 ?
3.5.1.14 N-chloroacetylglutamine-p-aminobenzoate + H2O
-
 Streptomyces sp. ?
-
 ?
3.5.1.14 N-chloroacetyltryptophan + H2O
-
 Streptomyces sp. chloroacetate + tryptophan
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.14 D-Aminoacylase
-
 Streptomyces sp.