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Literature summary extracted from
- Studies on the heparin sulphamidase activity from rat spleen. Intracellular distribution and characterization of the enzyme (1974), Biochem. J., 139, 699-708.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.10.1.1 | additional information | overview | Mammalia | |
| 3.10.1.1 | additional information | overview | Rattus norvegicus | |
| 3.10.1.1 | nitrocatechol sulfate | - |
Rattus norvegicus |  |
| 3.10.1.1 | p-Nitrophenyl sulfate | - |
Rattus norvegicus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.10.1.1 | 0.009 | - |
heparin | - |
Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.10.1.1 | lysosome | - |
Rattus norvegicus | 5764 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | 120000 | - |
ultracentrifugation, spleen | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.10.1.1 | heparin + H2O | Rattus norvegicus | - |
? + sulfate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.10.1.1 | Mammalia | - |
- |
- |
| 3.10.1.1 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.10.1.1 | partial purification | Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.10.1.1 | spleen | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.10.1.1 | heparin + H2O | - |
Rattus norvegicus | ? + sulfate | - |
ir | |
| 3.10.1.1 | heparin + H2O | - |
Rattus norvegicus | ? + sulfate | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | 37 | - |
- |
Rattus norvegicus |
Temperature Range [°C]
| EC Number | Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | 25 | 70 | - |
Rattus norvegicus |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | - |
- |
stable at | Rattus norvegicus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | 5 | - |
- |
Rattus norvegicus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | 4.5 | 6 | - |
Mammalia |
| 3.10.1.1 | 4.5 | 6 | - |
Rattus norvegicus |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | 5 | 7.4 | stable between | Rattus norvegicus |
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