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Literature summary extracted from

  • Yazaki, K.; Heide, L.; Tabata, M.
    Formation of p-hydroxybenzoic acid from p-coumaric acid by cell free extract of Lithospermum erythrorhizon cell cultures (1991), Phytochemistry, 30, 2233-2236.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.2.1.64 ADP does not act as cofactor, but has some stimulatory effect Lithospermum erythrorhizon
1.2.1.64 AMP does not act as cofactor, but has some stimulatory effect Lithospermum erythrorhizon
1.2.1.64 ATP does not act as cofactor, but has some stimulatory effect, can partly be replaced by ADP or AMP Lithospermum erythrorhizon
1.2.1.64 CoA does not act as cofactor, but has some stimulatory effect Lithospermum erythrorhizon

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.64 cytoplasm
-
 Lithospermum erythrorhizon 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.64 4-hydroxybenzaldehyde + NAD+ + H2O Lithospermum erythrorhizon best substrate tested, non beta-oxidative pathway rather than beta-oxidation 4-hydroxybenzoate + NADH + H+
-
 ?
1.2.1.64 4-hydroxybenzaldehyde + NAD+ + H2O Lithospermum erythrorhizon M18 best substrate tested, non beta-oxidative pathway rather than beta-oxidation 4-hydroxybenzoate + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.64 Lithospermum erythrorhizon
-
-
-
1.2.1.64 Lithospermum erythrorhizon M18
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.64 cell culture
-
 Lithospermum erythrorhizon
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.64 2-hydroxybenzaldehyde + NAD+ + H2O very low activity Lithospermum erythrorhizon 2-hydroxybenzoate + NADH + H+
-
 ?
1.2.1.64 2-hydroxybenzaldehyde + NAD+ + H2O very low activity Lithospermum erythrorhizon M18 2-hydroxybenzoate + NADH + H+
-
 ?
1.2.1.64 3-hydroxybenzaldehyde + NAD+ + H2O 48% of the activity compared to 4-hydroxybenzaldehyde Lithospermum erythrorhizon 3-hydroxybenzoate + NADH + H+
-
 ?
1.2.1.64 3-hydroxybenzaldehyde + NAD+ + H2O 48% of the activity compared to 4-hydroxybenzaldehyde Lithospermum erythrorhizon M18 3-hydroxybenzoate + NADH + H+
-
 ?
1.2.1.64 4-hydroxybenzaldehyde + NAD+ + H2O best substrate tested, non beta-oxidative pathway rather than beta-oxidation Lithospermum erythrorhizon 4-hydroxybenzoate + NADH + H+
-
 ?
1.2.1.64 4-hydroxybenzaldehyde + NAD+ + H2O best substrate tested, non beta-oxidative pathway rather than beta-oxidation Lithospermum erythrorhizon M18 4-hydroxybenzoate + NADH + H+
-
 ?
1.2.1.64 benzaldehyde + NAD+ + H2O 37.5% of the activity compared to 4-hydroxybenzaldehyde Lithospermum erythrorhizon benzoate + NADH + H+
-
 ?
1.2.1.64 benzaldehyde + NAD+ + H2O 37.5% of the activity compared to 4-hydroxybenzaldehyde Lithospermum erythrorhizon M18 benzoate + NADH + H+
-
 ?
1.2.1.64 vanillin + NAD+ + H2O 12.7% of the activity compared to 4-hydroxybenzaldehyde Lithospermum erythrorhizon vanillate + NADH
-
 ?
1.2.1.64 vanillin + NAD+ + H2O 12.7% of the activity compared to 4-hydroxybenzaldehyde Lithospermum erythrorhizon M18 vanillate + NADH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.64 NAD+ absolute requirement, can not be replaced by NADP+ Lithospermum erythrorhizon