Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Fernandez, M.R.; Biosca, J.A.; Martinez, M.C.; Achkor, H.; Farres, J.; Pares, X.
    Formaldehyde dehydrogenase from yeast and plant: implications for the general functional and structural significance of class III alcohol dehydrogenase (1997), Adv. Exp. Med. Biol., 414, 373-381.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.284 0.0004
-
S-hydroxymethyl glutathione
-
Homo sapiens
1.1.1.284 0.00092
-
S-hydroxymethyl glutathione
-
Rattus norvegicus
1.1.1.284 0.002
-
S-hydroxymethyl glutathione
-
Pisum sativum
1.1.1.284 0.006
-
S-hydroxymethyl glutathione
-
Drosophila melanogaster
1.1.1.284 0.0065
-
NAD+ reaction with S-hydroxymethyl glutathione Pisum sativum
1.1.1.284 0.04
-
S-hydroxymethyl glutathione
-
Saccharomyces cerevisiae
1.1.1.284 0.094
-
S-hydroxymethyl glutathione
-
Escherichia coli
1.1.1.284 0.14
-
NAD+ reaction with S-hydroxymethyl glutathione Pisum sativum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.284 formaldehyde + glutathione + NAD+ Escherichia coli
-
S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+ Saccharomyces cerevisiae main enzymatic system responsible for the formaldehyde elimination S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+ Pisum sativum main enzymatic system responsible for the formaldehyde elimination S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+ Arabidopsis thaliana main enzymatic system responsible for the formaldehyde elimination S-formylglutathione + NADH + H+
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.284 Arabidopsis thaliana
-
-
-
1.1.1.284 Drosophila melanogaster
-
alcohol dehydrogenase III
-
1.1.1.284 Escherichia coli
-
alcohol dehydrogenase III
-
1.1.1.284 Homo sapiens
-
class II alcohol dehydrogenase
-
1.1.1.284 Pisum sativum
-
class III alcohol dehydrogenase
-
1.1.1.284 Rattus norvegicus
-
class II alcohol dehydrogenase
-
1.1.1.284 Saccharomyces cerevisiae
-
class III alcohol dehydrogenase
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.284 formaldehyde + glutathione + NAD+
-
Drosophila melanogaster S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+
-
Escherichia coli S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+
-
Arabidopsis thaliana S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+ the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione Homo sapiens S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+ the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione Rattus norvegicus S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+ the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione Saccharomyces cerevisiae S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+ the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione Pisum sativum S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+ main enzymatic system responsible for the formaldehyde elimination Saccharomyces cerevisiae S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+ main enzymatic system responsible for the formaldehyde elimination Pisum sativum S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + glutathione + NAD+ main enzymatic system responsible for the formaldehyde elimination Arabidopsis thaliana S-formylglutathione + NADH + H+
-
?
1.1.1.284 formaldehyde + S-hydroxymethyl glutathione + NAD+
-
Drosophila melanogaster ?
-
?
1.1.1.284 formaldehyde + S-hydroxymethyl glutathione + NAD+
-
Escherichia coli ?
-
?
1.1.1.284 formaldehyde + S-hydroxymethyl glutathione + NAD+
-
Homo sapiens ?
-
?
1.1.1.284 formaldehyde + S-hydroxymethyl glutathione + NAD+
-
Rattus norvegicus ?
-
?
1.1.1.284 formaldehyde + S-hydroxymethyl glutathione + NAD+
-
Saccharomyces cerevisiae ?
-
?
1.1.1.284 formaldehyde + S-hydroxymethyl glutathione + NAD+
-
Pisum sativum ?
-
?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.1.1.284 3.33
-
S-hydroxymethyl glutathione
-
Homo sapiens
1.1.1.284 3.6
-
S-hydroxymethyl glutathione
-
Rattus norvegicus
1.1.1.284 6.33
-
S-hydroxymethyl glutathione
-
Pisum sativum
1.1.1.284 16
-
S-hydroxymethyl glutathione
-
Drosophila melanogaster
1.1.1.284 88.3
-
S-hydroxymethyl glutathione
-
Saccharomyces cerevisiae
1.1.1.284 156
-
S-hydroxymethyl glutathione
-
Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.284 NAD+
-
Drosophila melanogaster
1.1.1.284 NAD+
-
Escherichia coli
1.1.1.284 NAD+
-
Homo sapiens
1.1.1.284 NAD+
-
Rattus norvegicus
1.1.1.284 NAD+
-
Saccharomyces cerevisiae
1.1.1.284 NAD+
-
Pisum sativum
1.1.1.284 NAD+
-
Arabidopsis thaliana