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Literature summary extracted from

  • Rose, Z.B.; Racker, E.
    Formaldehyde dehydrogenase (1966), Methods Enzymol., 9, 357-360.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.284 formaldehyde
-
 Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.284 0.068
-
 NAD+
-
 Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.284 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.284
-
 Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.284 0.64
-
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.284 formaldehyde + glutathione + NAD+
-
 Saccharomyces cerevisiae S-formylglutathione + NADH + H+
-
 r
1.1.1.284 glyoxal + glutathione + NAD+
-
 Saccharomyces cerevisiae S-oxoacetylglutathione + NADH
-
 ?
1.1.1.284 methylglyoxal + glutathione + NAD+
-
 Saccharomyces cerevisiae S-pyruvylglutathione + NADH
-
 ?
1.1.1.284 S-formylglutathione + NADH
-
 Saccharomyces cerevisiae formaldehyde + glutathione + NAD+
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.284 8
-
-
 Saccharomyces cerevisiae

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.1.1.284 6 8.5 active from pH 6.0 to pH 8.5 Saccharomyces cerevisiae

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.284 NAD+
-
 Saccharomyces cerevisiae
1.1.1.284 NADH
-
 Saccharomyces cerevisiae
1.1.1.284 NADP+ no activity with NADP+ Saccharomyces cerevisiae