EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.1.3.6 | Long-chain alcohols | maximum activation with decanol and undecanol, shorter and longer alcohols are less effective | Schizophyllum commune |
EC Number | General Stability | Organism |
---|---|---|
1.1.3.6 | long-chain primary alcohols stabilize | Schizophyllum commune |
1.1.3.6 | SDS, 0.2 mM, stabilizes | Schizophyllum commune |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.3.6 | 0.2 | - |
cholesterol | - |
Schizophyllum commune | |
1.1.3.6 | 0.25 | - |
beta-sitosterol | in the presence of undecanol | Schizophyllum commune | |
1.1.3.6 | 0.45 | - |
stigmasterol | - |
Schizophyllum commune | |
1.1.3.6 | 0.5 | - |
pregnenolone | - |
Schizophyllum commune | |
1.1.3.6 | 0.5 | - |
beta-sitosterol | - |
Schizophyllum commune | |
1.1.3.6 | 1 | - |
cholesterol | in the presence of undecanol | Schizophyllum commune | |
1.1.3.6 | 1 | - |
dehydroepiandrosterone | in the presence and absence of undecanol | Schizophyllum commune | |
1.1.3.6 | 2 | - |
cholesterol | in the presence of undecanol | Schizophyllum commune | |
1.1.3.6 | 4 | - |
pregnenolone | in the presence of undecanol | Schizophyllum commune |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.3.6 | cholesterol + O2 | Schizophyllum commune | - |
cholest-5-en-3-one + H2O2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.3.6 | Schizophyllum commune | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.1.3.6 | cholesterol + O2 = cholest-5-en-3-one + H2O2 | bifunctional enzyme, catalyzes both the oxidation of DELTA5-ene-3beta hydroxysteroids with a trans A-B ring junction to the corresponding DELTA5-3-ketosteroid with the reduction of oxygen to hydrogen peroxide, and the isomerization to the DELTA4-3-ketosteroid | Schizophyllum commune |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.3.6 | beta-sitosterol + O2 | - |
Schizophyllum commune | stigmast-5-en-3-one + H2O2 | - |
? | |
1.1.3.6 | cholesterol + O2 | - |
Schizophyllum commune | cholest-4-en-3-one + H2O2 | - |
? | |
1.1.3.6 | cholesterol + O2 | - |
Schizophyllum commune | cholest-5-en-3-one + H2O2 | - |
? | |
1.1.3.6 | dehydroepiandrosterone + O2 | - |
Schizophyllum commune | androst-5-en-3,17-dione + H2O2 | - |
? | |
1.1.3.6 | pregnenolone + O2 | - |
Schizophyllum commune | 5-pregnen-3,20-dione + H2O2 | - |
? | |
1.1.3.6 | stigmasterol + O2 | - |
Schizophyllum commune | stigmasta-5,22-dien-3-one + H2O2 | - |
? |