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Literature summary extracted from

  • Sellinger, O.Z.; Miller, O.N.
    The metabolism of acetol phosphate. II. 1,2-Propanediol-1-phosphate dehydrogenase (1959), J. Biol. Chem., 234, 1641-1646.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.7 Br-
-
 Oryctolagus cuniculus
1.1.1.7 formate
-
 Oryctolagus cuniculus
1.1.1.7 SO32-
-
 Oryctolagus cuniculus
1.1.1.7 SO42-
-
 Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.7 5.5
-
 Hydroxyacetone phosphate
-
 Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.7 propane-1,2-diol-1-phosphate + NAD+ Oryctolagus cuniculus
-
 hydroxyacetone phosphate + NADH
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.7 Oryctolagus cuniculus
-
 rabbit
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.7 partial Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.7 muscle
-
 Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.7 0.3
-
 0.1-0.43 Oryctolagus cuniculus

Storage Stability

EC Number Storage Stability Organism
1.1.1.7 4°C, dialyzed against Tris-buffer, pH 7.7, 80% loss of activity in 1 month Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.7 hydroxyacetone phosphate + NADH
-
 Oryctolagus cuniculus propane-1,2-diol-1-phosphate + NAD+
-
 r
1.1.1.7 propane-1,2-diol-1-phosphate + NAD+
-
 Oryctolagus cuniculus hydroxyacetone phosphate + NADH
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.7 additional information
-
 dehydrogenation of propane-1,2-diol 1-phosphate has alkaline pH-optimum Oryctolagus cuniculus
1.1.1.7 7.7
-
 hydroxyacetone phosphate reduction Oryctolagus cuniculus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.1.1.7 5.4 9.6 hydroxyacetone phosphate reduction, values strongly dependent on buffer system Oryctolagus cuniculus