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Literature summary extracted from

  • Pirrung, M.C.; Chen, J.; Rowley, E.G.; McPhall, A.T.
    Mechanistic and stereochemical study of phenylpyruvate tautomerase (1993), J. Am. Chem. Soc., 115, 7103-7110.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.2.1 (E)-2-Fluoro-p-hydroxycinnamic acid
-
 Sus scrofa
5.3.2.1 (E)-2-Fluorocinnamic acid
-
 Sus scrofa
5.3.2.1 (E)-cinnamic acid
-
 Sus scrofa
5.3.2.1 (E)-p-hydroxycinnamic acid
-
 Sus scrofa
5.3.2.1 (p-Hydroxybenzylidene)malonate
-
 Sus scrofa
5.3.2.1 (Z)-2-Fluorocinnamic acid
-
 Sus scrofa
5.3.2.1 (Z)-cinnamic acid
-
 Sus scrofa
5.3.2.1 (Z)-Fluoro-p-hydroxycinnamic acid
-
 Sus scrofa
5.3.2.1 (Z)-p-hydroxycinnamic acid
-
 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.3.2.1 0.072
-
 (4-hydroxyphenyl)pyruvate enol-form, kidney Sus scrofa
5.3.2.1 2.2
-
 (4-hydroxyphenyl)pyruvate keto-form, kidney Sus scrofa
5.3.2.1 6.1
-
 phenylpyruvate keto-form, kidney Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
5.3.2.1 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.2.1 kidney
-
 Sus scrofa
-
5.3.2.1 thyroid gland
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.2.1 (Diiodohydroxyphenyl)pyruvate keto-form Sus scrofa ?
-
 ?
5.3.2.1 3-(4-hydroxyphenyl)pyruvate keto-form Sus scrofa 2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoate enol-form ?
5.3.2.1 Phenylpyruvate r Sus scrofa Phenylpyruvate
-
 ?
5.3.2.1 Phenylpyruvate keto-form Sus scrofa Phenylpyruvate
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
5.3.2.1 0.052
-
 (4-hydroxyphenyl)pyruvate enol-form, kidney Sus scrofa
5.3.2.1 0.45
-
 phenylpyruvate keto-form, kidney Sus scrofa
5.3.2.1 1.89
-
 (4-hydroxyphenyl)pyruvate keto-form, kidney Sus scrofa