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Literature summary extracted from
- Tartaric acid metabolism. 8. Crystalline tartronic semialdehyde reductase (1968), J. Biol. Chem., 243, 4426-4433.
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 1.1.1.60 | - |
Pseudomonas putida |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.60 | beta-Mercaptopyruvate | - |
Pseudomonas putida |  |
| 1.1.1.60 | Dihydroxyfumarate | - |
Pseudomonas putida | |
| 1.1.1.60 | glycolate | - |
Pseudomonas putida | |
| 1.1.1.60 | malonic semialdehyde | - |
Pseudomonas putida | |
| 1.1.1.60 | Succinic semialdehyde | - |
Pseudomonas putida | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.60 | 0.02 | 0.027 | NADH | - |
Pseudomonas putida | |
| 1.1.1.60 | 0.036 | 0.05 | NADPH | - |
Pseudomonas putida | |
| 1.1.1.60 | 0.04 | - |
NAD+ | - |
Pseudomonas putida | |
| 1.1.1.60 | 0.05 | 0.4 | D-glycerate | - |
Pseudomonas putida | |
| 1.1.1.60 | 0.05 | 0.4 | tartronate semialdehyde | - |
Pseudomonas putida | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.60 | 26000 | - |
4 * 26000, sedimentation velocity after treatment with guanidine hydrochloride and mercaptoethanol, amino acid analysis | Pseudomonas putida |
| 1.1.1.60 | 104000 | - |
sedimentation velocity | Pseudomonas putida |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.60 | tartronate semialdehyde + NAD(P)H | Pseudomonas putida | - |
(R)-glycerate + NAD(P)+ | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.60 | Pseudomonas putida | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.60 | - |
Pseudomonas putida |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.60 | 50 | - |
- |
Pseudomonas putida |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.60 | hydroxypyruvate + NAD(P)H + H+ | - |
Pseudomonas putida | glycerate + NAD(P)+ | - |
r | |
| 1.1.1.60 | tartronate semialdehyde + NAD(P)H | - |
Pseudomonas putida | (R)-glycerate + NAD(P)+ | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.1.1.60 | tetramer | 4 * 26000, sedimentation velocity after treatment with guanidine hydrochloride and mercaptoethanol, amino acid analysis | Pseudomonas putida |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.60 | 6 | - |
- |
Pseudomonas putida |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.60 | NAD+ | - |
Pseudomonas putida | |
| 1.1.1.60 | NADH | - |
Pseudomonas putida | |
| 1.1.1.60 | NADP+ | - |
Pseudomonas putida | |
| 1.1.1.60 | NADPH | - |
Pseudomonas putida | |
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