Any feedback?
Literature summary extracted from
- D-glucose-6-phosphate dehydrogenase (Entner-Doudoroff enzyme) from Pseudomonas fluorescens. Purification, properties and regulation (1975), Eur. J. Biochem., 59, 545-559.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.49 | acetyl-CoA | - |
Pseudomonas fluorescens |  |
| 1.1.1.49 | ADP | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | AMP | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | ATP | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | CoA | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | GTP | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | ITP | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | NADH | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | NADPH | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | phosphoenolpyruvate | - |
Pseudomonas fluorescens | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.49 | 220000 | - |
Entner-Doudoroff enzyme, gel chromatography | Pseudomonas fluorescens |
| 1.1.1.49 | 265000 | - |
Zwischenferment, gel chromatography | Pseudomonas fluorescens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.49 | D-glucose 6-phosphate + H2O + NADP+ | Pseudomonas fluorescens | - |
D-gluconate 6-phosphate + NADPH + H+ | 6-phosphoglucono-delta-lactone | r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.49 | Pseudomonas fluorescens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.49 | - |
Pseudomonas fluorescens |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.49 | additional information | - |
- |
Pseudomonas fluorescens |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 1.1.1.49 | 4°C, several months | Pseudomonas fluorescens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.49 | D-glucose 6-phosphate + H2O + NADP+ | - |
Pseudomonas fluorescens | D-gluconate 6-phosphate + NADPH + H+ | 6-phosphoglucono-delta-lactone | r | |
| 1.1.1.49 | D-glucose 6-phosphate + NAD+ | - |
Pseudomonas fluorescens | D-glucono-1,5-lactone 6-phosphate + NADH + H+ | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.49 | 30 | - |
assay at | Pseudomonas fluorescens |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.49 | 1120 | - |
NADP+ | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | 1380 | - |
NAD+ | - |
Pseudomonas fluorescens | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.49 | 8.9 | - |
- |
Pseudomonas fluorescens |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.49 | 6.5 | 10 | Entner-Doudoroff enzyme stable | Pseudomonas fluorescens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.49 | NAD+ | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | NADP+ | - |
Pseudomonas fluorescens | |
| 1.1.1.49 | NADPH | - |
Pseudomonas fluorescens | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
