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Literature summary extracted from

  • Pearse, B.M.F.; Harris, J.I.
    6-Phosphogluconate dehydrogenase from Bacillus stearothermophilus (1973), FEBS Lett., 38, 49-52.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.44
-
Geobacillus stearothermophilus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.44 iodoacetamide
-
Geobacillus stearothermophilus
1.1.1.44 iodoacetamide
-
Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.44 50000
-
2 * 50000, SDS-PAGE Geobacillus stearothermophilus
1.1.1.44 100000
-
-
Cyberlindnera jadinii
1.1.1.44 100000
-
sedimentation equilibrium Geobacillus stearothermophilus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.44 6-phospho-D-gluconate + NADP+ Cyberlindnera jadinii
-
D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r
1.1.1.44 6-phospho-D-gluconate + NADP+ Homo sapiens
-
D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r
1.1.1.44 6-phospho-D-gluconate + NADP+ Geobacillus stearothermophilus
-
D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r
1.1.1.44 6-phospho-D-gluconate + NADP+ Geobacillus stearothermophilus NCA 1503
-
D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.44 Cyberlindnera jadinii
-
-
-
1.1.1.44 Geobacillus stearothermophilus
-
NCA 1503
-
1.1.1.44 Geobacillus stearothermophilus NCA 1503
-
NCA 1503
-
1.1.1.44 Homo sapiens
-
human
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.44
-
Geobacillus stearothermophilus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.44 erythrocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.44 6-phospho-D-gluconate + NADP+
-
Cyberlindnera jadinii D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
Homo sapiens D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
Geobacillus stearothermophilus D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
Geobacillus stearothermophilus NCA 1503 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r

Subunits

EC Number Subunits Comment Organism
1.1.1.44 dimer
-
Cyberlindnera jadinii
1.1.1.44 dimer
-
Homo sapiens
1.1.1.44 dimer 2 * 50000, SDS-PAGE Geobacillus stearothermophilus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.44 60
-
-
Geobacillus stearothermophilus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
1.1.1.44 25 70 retains full activity at 60°C Geobacillus stearothermophilus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.1.1.44 70
-
stable at relatively high temperatures Geobacillus stearothermophilus