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Literature summary extracted from

  • Ma, H.; Kubicek, C.P.; Roehr, M.
    Malate dehydrogenase isoenzymes in Aspergillus niger (1981), FEMS Microbiol. Lett., 12, 147-151.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.37 ATP
-
 Aspergillus niger
1.1.1.37 oxaloacetate
-
 Aspergillus niger

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.37 0.083
-
 oxaloacetate mitochondrial MDH Aspergillus niger
1.1.1.37 0.09
-
 oxaloacetate cyt MDH Aspergillus niger
1.1.1.37 0.14
-
 NADH mit MDH Aspergillus niger
1.1.1.37 0.192
-
 NADH cytosolic MDH Aspergillus niger

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.37 cytoplasm
-
 Aspergillus niger 5737
-
1.1.1.37 mitochondrion
-
 Aspergillus niger 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.37 35000
-
 2 * 35000, SDS-PAGE Aspergillus niger
1.1.1.37 68000
-
 gel filtration Aspergillus niger

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.37 malate + NAD+ Aspergillus niger
-
 oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+ Aspergillus niger B60
-
 oxaloacetate + NADH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.37 Aspergillus niger
-
-
-
1.1.1.37 Aspergillus niger B60
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.37 2 isoenzymes, cytoplasmic and mitochondrial Aspergillus niger

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.37 (S)-malate + NAD+
-
 Aspergillus niger oxaloacetate + NADH + H+
-
 r
1.1.1.37 (S)-malate + NAD+
-
 Aspergillus niger B60 oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+
-
 Aspergillus niger oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+
-
 Aspergillus niger B60 oxaloacetate + NADH + H+
-
 r
1.1.1.37 oxaloacetate + NADH
-
 Aspergillus niger L-malate + NAD+
-
 r
1.1.1.37 oxaloacetate + NADH
-
 Aspergillus niger B60 L-malate + NAD+
-
 r

Subunits

EC Number Subunits Comment Organism
1.1.1.37 dimer 2 * 35000, SDS-PAGE Aspergillus niger