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Literature summary extracted from

  • Betsche, T.
    L-Lactate dehydrogenase from leaves of higher plants. Kinetics and regulation of the enzyme from lettuce (Lactuca sativa L) (1981), Biochem. J., 195, 615-622.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.27 3-phosphoglycerate
-
 Lactuca sativa
1.1.1.27 ADP
-
 Lactuca sativa
1.1.1.27 Ala
-
 Lactuca sativa
1.1.1.27 AMP
-
 Lactuca sativa
1.1.1.27 ATP competitive with respect to NADH at pH 7.0 and at pH 6.2 Lactuca sativa
1.1.1.27 citrate
-
 Lactuca sativa
1.1.1.27 fructose 1,6-diphosphate
-
 Lactuca sativa
1.1.1.27 glucose 6-phosphate
-
 Lactuca sativa
1.1.1.27 Gly
-
 Lactuca sativa
1.1.1.27 isocitrate
-
 Lactuca sativa
1.1.1.27 oxalate
-
 Lactuca sativa
1.1.1.27 Ser
-
 Lactuca sativa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.27 0.35
-
 pyruvate pH 6.2 Lactuca sativa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.27 additional information Lactuca sativa the enzyme is a component of the system regulating the cellular pH and/or controlling the concentration of reducing equivalents in the cytoplasm of leaf cells ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.27 Lactuca sativa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.27
-
 Lactuca sativa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.27 leaf
-
 Lactuca sativa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.27 additional information
-
-
 Lactuca sativa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.27 (S)-lactate + NAD+
-
 Lactuca sativa pyruvate + NADH + H+
-
 r
1.1.1.27 glyoxylate + NADH
-
 Lactuca sativa glycolate + NAD+
-
 ?
1.1.1.27 hydroxypyruvate + NADPH + H+
-
 Lactuca sativa 2,3-dihydroxypropanoate + NADP+
-
 ?
1.1.1.27 additional information the enzyme is a component of the system regulating the cellular pH and/or controlling the concentration of reducing equivalents in the cytoplasm of leaf cells Lactuca sativa ?
-
 ?
1.1.1.27 pyruvate + NADH + H+
-
 Lactuca sativa (S)-lactate + NAD+
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.27 NAD+ coenzyme Lactuca sativa
1.1.1.27 NADH coenzyme Lactuca sativa