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Literature summary extracted from

  • Grolle, S.; Bringer-Meyer, S.; Sahm, H.
    Isolation of the dxr gene of Zymomonas mobilis and characterization of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase (2000), FEMS Microbiol. Lett., 191, 131-137.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.267 overexpression in Escherichia coli Zymomonas mobilis

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.267 EDTA
-
 Zymomonas mobilis
1.1.1.267 Fe2+
-
 Zymomonas mobilis
1.1.1.267 fosmidomycin
-
 Zymomonas mobilis
1.1.1.267 Ni2+
-
 Zymomonas mobilis
1.1.1.267 Zn2+
-
 Zymomonas mobilis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.267 0.3
-
 1-deoxy-D-xylulose 5-phosphate
-
 Zymomonas mobilis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.1.267 additional information divalent cations required for acitvity, activity decreases in the following order: Co2+, Mn2+, Mg2+, Ba2+, Ca2+, Cu2+ Zymomonas mobilis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.267 39000
-
 2 * 39000, SDS-PAGE Zymomonas mobilis
1.1.1.267 108000
-
 gel filtration Zymomonas mobilis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.267 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ Zymomonas mobilis
-
 2-C-methyl-D-erythritol 4-phosphate + NADP+
-
 ir

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.267 Zymomonas mobilis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.267 of recombinant protein Zymomonas mobilis

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.267 19.5
-
-
 Zymomonas mobilis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.267 1-deoxy-D-xylulose 5-phosphate + NADPH + H+
-
 Zymomonas mobilis 2-C-methyl-D-erythritol 4-phosphate + NADP+
-
 ir

Subunits

EC Number Subunits Comment Organism
1.1.1.267 dimer 2 * 39000, SDS-PAGE Zymomonas mobilis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.267 7 8
-
 Zymomonas mobilis

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.267 NADP+
-
 Zymomonas mobilis