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Literature summary extracted from

  • Grubb, M.F.; Kasofsky, J.; Strong, J.; Anderson, L.W.; Cysyk, R.L.
    Serum stimulation of UDP-glucose dehydrogenase activity in swiss 3T3 fibroblasts (1993), Biochem. Mol. Biol. Int., 30, 819-827.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.22 additional information fetal calf serum stimulates enzyme activity Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.22 UDP-D-xylose
-
 Homo sapiens
1.1.1.22 UDPglucuronate product feed-back inhibition competitive with UDPglucose Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.22 0.108
-
 UDPglucose
-
 Homo sapiens
1.1.1.22 0.17
-
 NAD+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.22 UDPglucose + NAD+ + H2O Homo sapiens
-
 UDPglucuronate + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.22 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.22 fibroblast cell line enzyme activity depends on growth phase of the culture Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.22 UDP-glucose + 2 NAD+ + H2O
-
 Homo sapiens UDP-glucuronate + 2 NADH + 2 H+
-
 ?
1.1.1.22 UDPglucose + NAD+ + H2O
-
 Homo sapiens UDPglucuronate + NADH
-
 ?