Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Clements, R.S.; Winegrad, A.I.
    Purification of alditol: NADP oxidoreductase from human placenta (1972), Biochem. Biophys. Res. Commun., 47, 1473-1479.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.21 (NH4)2SO4 activation Homo sapiens
1.1.1.21 (NH4)2SO4 0.1 M Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.21 3,3-Tetramethylene glutaric acid
-
 Homo sapiens
1.1.1.21 3-hydroxybutyrate
-
 Homo sapiens
1.1.1.21 3-hydroxybutyric acid
-
 Homo sapiens
1.1.1.21 NaCl
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.1.21 Li2SO4 stimulation Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.21 39000
-
 sucrose density gradient centrifugation, thin layer gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.21 aldose + NAD(P)H Homo sapiens
-
 alditol + NAD(P)+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.21 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.21
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.21 placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.21 1.68
-
-
 Homo sapiens

Storage Stability

EC Number Storage Stability Organism
1.1.1.21 4°C, 2 weeks in 1% ampholines Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.21 alditol + NAD(P)+
-
 Homo sapiens aldose + NAD(P)H
-
 r
1.1.1.21 aldose + NAD(P)H
-
 Homo sapiens alditol + NAD(P)+
-
 r
1.1.1.21 D-erythrose + NAD(P)H
-
 Homo sapiens erythritol + NAD(P)+
-
 r
1.1.1.21 D-galactose + NAD(P)H
-
 Homo sapiens dulcitol + NAD(P)+
-
 r
1.1.1.21 D-glucose + NAD(P)H
-
 Homo sapiens sorbitol + NAD(P)+
-
 r
1.1.1.21 D-glucuronolactone + NADPH
-
 Homo sapiens ?
-
 ?
1.1.1.21 D-ribose + NAD(P)H
-
 Homo sapiens ribitol + NAD(P)+
-
 r
1.1.1.21 D-xylose + NAD(P)H
-
 Homo sapiens xylitol + NAD(P)+
-
 r
1.1.1.21 L-arabinose + NAD(P)H
-
 Homo sapiens L-arabitol + NAD(P)+
-
 r
1.1.1.21 xylitol + NAD(P)+
-
 Homo sapiens D-xylose + NAD(P)H + H+
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.21 5.8 6.7
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.21 NADPH
-
 Homo sapiens