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Literature summary extracted from

  • Katoh, S.; Arai, Y.; Taketani, T.; Yamada, S.
    Sepiapterin reductase in blood of various animals and of leukemic rats (1974), Biochim. Biophys. Acta, 370, 378-388.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH Gallus gallus
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH Cavia porcellus
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH Mus musculus
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH Rattus norvegicus
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH Sus scrofa
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH Oryctolagus cuniculus
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH Canis lupus familiaris
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH Rattus norvegicus Donryu
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH Rattus norvegicus Sprague-Dawley
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.153 Canis lupus familiaris
-
-
-
1.1.1.153 Cavia porcellus
-
 low activity
-
1.1.1.153 Gallus gallus
-
-
-
1.1.1.153 Mus musculus
-
-
-
1.1.1.153 Oryctolagus cuniculus
-
 low activity
-
1.1.1.153 Rattus norvegicus
-
 Sprague-Dawley
-
1.1.1.153 Rattus norvegicus
-
 Donryu
-
1.1.1.153 Rattus norvegicus Donryu
-
 Donryu
-
1.1.1.153 Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley
-
1.1.1.153 Sus scrofa
-
 low activity
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.153 blood
-
 Gallus gallus
-
1.1.1.153 blood
-
 Cavia porcellus
-
1.1.1.153 blood
-
 Mus musculus
-
1.1.1.153 blood
-
 Rattus norvegicus
-
1.1.1.153 blood
-
 Sus scrofa
-
1.1.1.153 blood
-
 Oryctolagus cuniculus
-
1.1.1.153 blood
-
 Canis lupus familiaris
-
1.1.1.153 erythrocyte
-
 Gallus gallus
-
1.1.1.153 erythrocyte
-
 Cavia porcellus
-
1.1.1.153 erythrocyte
-
 Mus musculus
-
1.1.1.153 erythrocyte
-
 Rattus norvegicus
-
1.1.1.153 erythrocyte
-
 Sus scrofa
-
1.1.1.153 erythrocyte
-
 Oryctolagus cuniculus
-
1.1.1.153 erythrocyte
-
 Canis lupus familiaris
-
1.1.1.153 liver
-
 Mus musculus
-
1.1.1.153 liver
-
 Rattus norvegicus
-
1.1.1.153 additional information not in leukocytes and ascites tumor cells Gallus gallus
-
1.1.1.153 additional information not in leukocytes and ascites tumor cells Cavia porcellus
-
1.1.1.153 additional information not in leukocytes and ascites tumor cells Mus musculus
-
1.1.1.153 additional information not in leukocytes and ascites tumor cells Rattus norvegicus
-
1.1.1.153 additional information not in leukocytes and ascites tumor cells Sus scrofa
-
1.1.1.153 additional information not in leukocytes and ascites tumor cells Oryctolagus cuniculus
-
1.1.1.153 additional information not in leukocytes and ascites tumor cells Canis lupus familiaris
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Gallus gallus 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Cavia porcellus 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Mus musculus 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Rattus norvegicus 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Sus scrofa 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Oryctolagus cuniculus 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Canis lupus familiaris 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Rattus norvegicus Donryu 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Rattus norvegicus Sprague-Dawley 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.153 NADPH
-
 Gallus gallus
1.1.1.153 NADPH
-
 Cavia porcellus
1.1.1.153 NADPH
-
 Mus musculus
1.1.1.153 NADPH
-
 Rattus norvegicus
1.1.1.153 NADPH
-
 Sus scrofa
1.1.1.153 NADPH
-
 Oryctolagus cuniculus
1.1.1.153 NADPH
-
 Canis lupus familiaris