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Literature summary extracted from

  • Hausman, S.Z.; London, J.
    Purification and characterization of ribitol-5-phosphate and xylitol-5-phosphate dehydrogenases from strains of Lactobacillus casei (1987), J. Bacteriol., 169, 1651-1655.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.137 ATP
-
 Lacticaseibacillus casei

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.137 0.025
-
 NAD+
-
 Lacticaseibacillus casei
1.1.1.137 0.66
-
 D-ribitol 5-phosphate
-
 Lacticaseibacillus casei

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.137 49000
-
 2 * 49000, denaturing PAGE Lacticaseibacillus casei
1.1.1.137 115000
-
 gel filtration Lacticaseibacillus casei

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.137 Lacticaseibacillus casei
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.137
-
 Lacticaseibacillus casei

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.137 additional information
-
-
 Lacticaseibacillus casei

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.137 D-ribitol 5-phosphate + NAD+
-
 Lacticaseibacillus casei D-ribulose 5-phosphate + NADH
-
 r
1.1.1.137 D-ribulose 5-phosphate + NADH + H+
-
 Lacticaseibacillus casei D-ribitol 5-phosphate + NAD+
-
 r

Subunits

EC Number Subunits Comment Organism
1.1.1.137 dimer 2 * 49000, denaturing PAGE Lacticaseibacillus casei

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.137 5.5 6.5 D-ribitol 5-phosphate + NAD+ Lacticaseibacillus casei
1.1.1.137 8 9 D-ribulose 5-phosphate + NADH Lacticaseibacillus casei

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.137 NAD+ absolutely specific for NAD+ Lacticaseibacillus casei
1.1.1.137 NADH cofactor Lacticaseibacillus casei
1.1.1.137 NADP+ no activity with Lacticaseibacillus casei