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Literature summary extracted from

  • Schiwara, H.W.; Domschke, W.; Domagk, G.F.
    Differenzierung verschiedener Zucker-Dehydrogenasen in der Schweineleber durch Disk-Elektrophorese und Ionenaustauschchromatograpie (1968), Hoppe-Seyler's Z. Physiol. Chem., 349, 1575-1581.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.115 HgCl2 2.5 mM, 94% inhibition Sus scrofa
1.1.1.115 iodoacetamide 200 mM, 90% inhibition Sus scrofa
1.1.1.115 NEM 10 mM, 81% inhibition Sus scrofa
1.1.1.115 p-chloromercuribenzoate 0.2 mM, 92% inhibition Sus scrofa
1.1.1.116 HgCl2
-
 Sus scrofa
1.1.1.116 iodoacetamide
-
 Sus scrofa
1.1.1.116 N-ethylmaleimide
-
 Sus scrofa
1.1.1.116 p-chloromercuribenzoate
-
 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.115 1.4
-
 D-xylose
-
 Sus scrofa
1.1.1.115 7.7
-
 D-arabinose
-
 Sus scrofa
1.1.1.115 8
-
 D-ribose
-
 Sus scrofa
1.1.1.116 0.017
-
 NAD+
-
 Sus scrofa
1.1.1.116 20
-
 D-arabinose
-
 Sus scrofa
1.1.1.116 24
-
 2-deoxy-D-ribose
-
 Sus scrofa
1.1.1.116 49
-
 digitoxose
-
 Sus scrofa
1.1.1.116 670
-
 D-ribose
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.115 Sus scrofa
-
-
-
1.1.1.116 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.116 partial Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.115 liver
-
 Sus scrofa
-
1.1.1.116 liver
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.115 D-arabinose + NADP+ + H2O
-
 Sus scrofa ?
-
 ?
1.1.1.115 D-ribose + NADP+ + H2O
-
 Sus scrofa D-ribonate + NADPH
-
 ?
1.1.1.115 D-xylose + NADP+ + H2O
-
 Sus scrofa ?
-
 ?
1.1.1.116 2-deoxy-D-ribose + NAD+
-
 Sus scrofa 2-deoxy-D-ribono-1,4-lactone + NADH
-
 ?
1.1.1.116 D-arabinose + NAD+
-
 Sus scrofa D-arabinono-1,4-lactone + NADH
-
 ?
1.1.1.116 D-lyxose + NAD+
-
 Sus scrofa D-lyxono-1,5-lactone + NADH
-
 ?
1.1.1.116 D-ribose + NAD+
-
 Sus scrofa D-ribono-1,4-lactone + NADH
-
 ?
1.1.1.116 D-xylose + NAD+ poor substrate Sus scrofa D-xylono-1,4-lactone + NADH
-
 ?
1.1.1.116 digitoxose + NAD+
-
 Sus scrofa ?
-
 ?
1.1.1.116 L-arabinose + NAD+ poor substrate Sus scrofa L-arabinono-1,4-lactone + NADH
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.116 25
-
 assay at Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.115 9.7
-
-
 Sus scrofa
1.1.1.116 10.6
-
-
 Sus scrofa

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.1.1.115 9 10.3 about 55% of maximal activity at pH 9.0 and at pH 10.3 Sus scrofa
1.1.1.116 9.4 11.8 about 60% of maximal activity at pH 9.4 and 11.8 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.115 NADP+ cofactor Sus scrofa
1.1.1.116 NAD+
-
 Sus scrofa
1.1.1.116 NADP+ 66% as effective as NAD+ Sus scrofa