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Literature summary extracted from

  • Mori, N.; Kasugai, T.; Kitamoto, Y.; Ichikawa, Y.
    Purification and some properties of carnitine dehydrogenase from Xanthomonas translucens (1988), Agric. Biol. Chem., 52, 249-250.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.108 Ag+
-
 Xanthomonas translucens
1.1.1.108 Ca2+
-
 Xanthomonas translucens
1.1.1.108 Co2+
-
 Xanthomonas translucens
1.1.1.108 Cu2+
-
 Xanthomonas translucens
1.1.1.108 Hg+
-
 Xanthomonas translucens
1.1.1.108 Li+
-
 Xanthomonas translucens
1.1.1.108 Mn2+
-
 Xanthomonas translucens
1.1.1.108 Ni2+ strong inhibition Xanthomonas translucens
1.1.1.108 p-chloromercuribenzoate
-
 Xanthomonas translucens
1.1.1.108 Zn2+
-
 Xanthomonas translucens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.108 0.04
-
 NADH
-
 Xanthomonas translucens
1.1.1.108 0.25
-
 NAD+
-
 Xanthomonas translucens
1.1.1.108 1.71
-
 3-dehydrocarnitine
-
 Xanthomonas translucens
1.1.1.108 10
-
 L-carnitine
-
 Xanthomonas translucens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.108 37000
-
 2 * 37000, SDS-PAGE Xanthomonas translucens
1.1.1.108 74000
-
 gel filtration Xanthomonas translucens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.108 (R)-3-hydroxy-4-trimethylaminobutyrate + NAD+ Xanthomonas translucens
-
 3-dehydrocarnitine + NADH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.108 Xanthomonas translucens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.108 ammonium sulfate, DEAE-cellulose, Sephadex G-100, 5'-AMP Sepharose 4B, Sephadex G-100 Xanthomonas translucens

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.108 21
-
-
 Xanthomonas translucens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.108 (R)-3-hydroxy-4-trimethylaminobutyrate + NAD+
-
 Xanthomonas translucens 3-dehydrocarnitine + NADH + H+
-
 r
1.1.1.108 carnitine + NAD+
-
 Xanthomonas translucens 3-dehydrocarnitine + NADH + H+
-
 r

Subunits

EC Number Subunits Comment Organism
1.1.1.108 dimer 2 * 37000, SDS-PAGE Xanthomonas translucens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.108 6.5
-
 reduction of 3-dehydrocarnitine Xanthomonas translucens
1.1.1.108 9.5
-
 oxidation of L-carnitine Xanthomonas translucens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.108 NAD+
-
 Xanthomonas translucens