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Literature summary extracted from

  • Sheldon, P.S.; Safford, R.; Slabas, A.R.; Kekwick, R.G.O.
    3-Oxoacyl-[acyl carrier protein] reductase: a component of plant fatty acid synthase (1988), Biochem. Soc. Trans., 16, 392-393.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.100 3-oxoacyl-[acyl-carrier protein] + NADPH Brassica napus first reduction step of fatty acid synthase (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+
-
 ?
1.1.1.100 3-oxoacyl-[acyl-carrier protein] + NADPH Persea americana first reduction step of fatty acid synthase (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.100 Brassica napus
-
 oilseed
-
1.1.1.100 Persea americana
-
 avocado
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.100
-
 Brassica napus
1.1.1.100
-
 Persea americana

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.100 mesocarp
-
 Persea americana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.100 3-oxoacyl-[acyl-carrier protein] + NADPH
-
 Brassica napus (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+
-
 ?
1.1.1.100 3-oxoacyl-[acyl-carrier protein] + NADPH
-
 Persea americana (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+
-
 ?
1.1.1.100 3-oxoacyl-[acyl-carrier protein] + NADPH first reduction step of fatty acid synthase Brassica napus (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+
-
 ?
1.1.1.100 3-oxoacyl-[acyl-carrier protein] + NADPH first reduction step of fatty acid synthase Persea americana (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+
-
 ?
1.1.1.100 acetoacetyl-CoA + NADPH + H+
-
 Brassica napus D-beta-hydroxybutyryl-CoA + NADP+
-
 ?
1.1.1.100 acetoacetyl-CoA + NADPH + H+
-
 Persea americana D-beta-hydroxybutyryl-CoA + NADP+
-
 ?
1.1.1.100 acetoacetyl-N-cysteamine + NADPH
-
 Brassica napus D-3-hydroxybutyryl-N-cysteamine + NADP+
-
 ?
1.1.1.100 acetoacetyl-N-cysteamine + NADPH
-
 Persea americana D-3-hydroxybutyryl-N-cysteamine + NADP+
-
 ?
1.1.1.100 acetoacetyl-[acyl-carrier protein] + NADPH much greater specificity for acetoacetyl-ACP than for either of the model substrates acetoacetyl-CoA or acetoacetyl-N-acetylcysteamine Brassica napus D-beta-hydroxybutyryl-[acyl-carrier protein] + NADP+
-
 ?
1.1.1.100 acetoacetyl-[acyl-carrier protein] + NADPH much greater specificity for acetoacetyl-ACP than for either of the model substrates acetoacetyl-CoA or acetoacetyl-N-acetylcysteamine Persea americana D-beta-hydroxybutyryl-[acyl-carrier protein] + NADP+
-
 ?
1.1.1.100 additional information animals, yeast and Mycobacteria have fatty acid synthetase containing all the individual activities on one or two multifunctional polypeptide chains, plants and most bacterial systems, including E. coli, possess individual monofunctional enzymes and a separate acyl carrier protein Brassica napus ?
-
 ?
1.1.1.100 additional information animals, yeast and Mycobacteria have fatty acid synthetase containing all the individual activities on one or two multifunctional polypeptide chains, plants and most bacterial systems, including E. coli, possess individual monofunctional enzymes and a separate acyl carrier protein Persea americana ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.1.100 More animals, yeast and Mycobacteria have fatty acid synthetases containing all the individual activities on one or two multifunctional polypeptide chains, plants and most bacterial systems, including Escherichia coli, possess individual monofunctional enzymes and a separate acyl carrier protein Brassica napus
1.1.1.100 More animals, yeast and Mycobacteria have fatty acid synthetases containing all the individual activities on one or two multifunctional polypeptide chains, plants and most bacterial systems, including Escherichia coli, possess individual monofunctional enzymes and a separate acyl carrier protein Persea americana
1.1.1.100 tetramer
-
 Persea americana
1.1.1.100 tetramer 4 * 20000-30000, SDS-PAGE Brassica napus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.100 NADPH absolute specificity for NADPH Brassica napus
1.1.1.100 NADPH absolute specificity for NADPH Persea americana